Nguyen Phuc Binh, Dao Viet Hang, Tran Quoc Tien, Dao Van Long

Tóm tắt

Upper gastrointestinal bleeding is an emergency requiring immediate management and cooperation of many specialties. Among the causes of upper gastrointestinal bleeding, non-variceal upper gastrointestinal bleeding has the highest percentage. Initial assessment, prognosis factor classification and suitable interventions will help to reduce recurrent bleeding rate. The study aims to evaluate the characteristics of non-variceal upper gastrointestinal bleeding and identify correlating factors of recurrent bleeding. A retrospective descriptive study was conducted on non-variceal upper gastrointestinal bleeding patients admitted to Hanoi Medical University Hospital with ICD 10 code K92.2 from January 2013 to March 2017. There were 444 patients with the mean age of 49.1 (18.1). There were 69.8% of patients with co-morbidities in which 25.9% had history of upper gastrointestinal bleeding. The median Rockall score was 3 and the median Glasgow-Blatchford Bleeding Score (GBS) was 7. The rate of endoscopic interventions was 48.4% in which 99.1% achieved success. The rate of recurrent bleeding in hospital was 4.5% and within 30 days after discharge was 1.1%. There was no difference of recurrence in the groups performed mono and combined therapies. Glasgow-Blatchford Score and Rockall score had low prognosis performance for in-hospital recurrence. In conclusion, the rate of recurrence both in hospital and within 30 days in non-variceal upper gastrointestinal bleeding patients was low.


Từ khóa

non-variceal upper gastrointestinal bleeding; epidemiology; recurrent bleeding; related factors

Toàn văn:


Tài liệu tham khảo

Gralnek I., Dumonceau J-M., Kuipers E et al (2015). Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy, 47(10), a1 - 46.

Barkun AN., Bardou M., Kuipers EJ et al (2010). International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med, 152(2), 101 - 113.

Hreinsson JP., Kalaitzakis E., Gudmundsson S et al (2013). Upper gastrointestinal bleeding: incidence, etiology and outcomes in a population-based setting. Scand J Gastroenterol, 48(4), 439 - 447.

Rotondano G (2014). Epidemiology and Diagnosis of Acute Nonvariceal Upper Gastrointestinal Bleeding. Gastroenterol Clin North Am, 43(4), 643 - 63.

Van Leerdam ME (2008). Epidemiology of acute upper gastrointestinal bleeding. Best Pract Res Clin Gastroenterol, 22(2), 209 - 224.

Sengupta N., Tapper EB., Patwardhan VR et al (2016). High Glasgow Blatchford Score at admission is associated with recurrent bleeding after discharge for patients hospitalized with upper gastrointestinal bleeding. Endoscopy, 48(1), 9 - 15.

Minakari M., Badihian S., Jalalpour P et al (2017). Etiology and outcome in patients with upper gastrointestinal bleeding: Study on 4747 patients in the central region of Iran:

Upper gastrointestinal bleeding in Iran. J Gastroenterol Hepatol, 32(4), 789 - 796.

Long Dao Van (2015). A study on non-variceal upper gastrointestinal bleeding in 17 big hospitals of Vietnam. Vietnam Medical Journal, 426(1), 109.

Chiu PWY, Ng EKW, Cheung FKY et al (2009). Predicting Mortality in Patients With Bleeding Peptic Ulcers After Therapeutic Endoscopy. Clin Gastroenterol Hepatol, 7(3), 311 - 316.

Bunchorntavakul C., Yodket Y., Singhasena N (2017). Clinical Characteristics, Treatment Outcomes and Risk Assessment of Patients with Acute Upper Gastrointestinal Bleeding in Rajavithi Hospital, Thailand. J Med Assoc Thai, 100(2), 104.

Monteiro S (2016). Upper gastrointestinal bleeding risk scores: Who, when and why? World J Gastrointest Pathophysiol, 7(1), 86.

Bozkurt MA., Peker KD., Unsal MG et al (2017). The Importance of Rockall Scoring System for Upper Gastrointestinal Bleeding in Long-Term Follow-Up. Indian J Surg, 79(3), 188 - 191.