TY - JOUR AU - Van Anh, Pham Thi AU - Thanh, Nguyen Phuong AU - Duong, Dau Thuy AU - Thuy, Nguyen Thi AU - Mai, Dang Thi Ngoc AU - Chi, Nguyen Duc Linh AU - Thai, Nguyen Quang AU - Ba, Hoang Xuan AU - Huong, Hoang Thi AU - Anh, Tran Ngoc AU - Thanh, Duong Cong AU - Phuong Anh, Nguyen Thi PY - 2021/12/31 Y2 - 2024/03/28 TI - Efficacy and safety of Trang Phuc Linh Plus tablets in patients with irritable bowel syndrome-diarrhea JF - Tạp chí Nghiên cứu Y học JA - TCNCYH VL - 148 IS - 12 SE - DO - 10.52852/tcncyh.v148i12.588 UR - https://tapchinghiencuuyhoc.vn/index.php/tcncyh/article/view/588 SP - 68-77 AB - <p>A double-blind, randomized, phase II clinical trial was conducted within a 14-week follow-up including 2 weeks of the non-drug run-in period, 8 weeks of medication, and 4 weeks of follow-up after discontinuation. The objective of the study was to evaluate the efficacy and safety of Trang Phuc Linh Plus in irritable diarrhea syndrome patients. Group I took Trang Phuc Linh Plus 3 tablets/time x 2 times/day for 8 weeks; Group II took placebo 3 tablets/time x 2 times/day for 8 weeks. Patients will be re-examined, tested, and evaluated over the phone for symptom recurrence and adverse events (AEs). This study showed that the Trang Phuc Linh Plus tablets tended to improve symptoms in patients suffering from irritable bowel syndrome with diarrhea, suggesting its safety and tolerability. </p> ER -