25. Solitary metastasis to the pancreas from colon cancer treated with radical surgery: A case report and literature review

Pham The Anh, Truong Manh Cuong, Pham Tuan Anh

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Tóm tắt

This report describes a rare case of pancreatic metastasis in a 56-year-old woman with a past medical history of malignancy. The patient initially presented with right breast cancer in 2008, which was treated with a modified radical mastectomy followed by adjuvant chemotherapy. Subsequently, she developed right colon cancer and underwent a right hemicolectomy with adjuvant chemotherapy in 2015. In October 2020, during a routine examination, a suspicious lesion was identified in the duodenum and head of the pancreas. A biopsy confirmed the presence of moderately differentiated adenocarcinoma. Following a comprehensive multidisciplinary consultation, the patient was recommended for exploratory surgery to assess the feasibility of a pancreatoduodenectomy (Whipple procedure) with subsequent ileocolic reanastomosis (reconnection of the ileum to the transverse colon), followed by systemic therapy.

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Tài liệu tham khảo

1. Nakamura E, Shimizu M, Itoh T, Manabe T. Secondary tumors of the pancreas: a clinicopathological study of 103 autopsy cases of Japanese patients. Pathology international. 2001; 51(9): 686-690.
2. Rumancik WM, Megibow AJ, Bosniak MA, Hilton S. Metastatic disease to the pancreas: evaluation by computed tomography. Journal of computer-assisted tomography. 1984; 8(5): 829-834.
3. Roland CF, Van Heerden J. Nonpancreatic primary tumors with metastasis to the pancreas. Surgery, gynecology & obstetrics. 1989; 168(4): 345-347.
4. Matsubara N, Baba H, Okamoto A, et al. Rectal cancer metastasis to the head of the pancreas treated with pancreaticoduodenectomy. Journal of Hepato-Biliary-Pancreatic Surgery. 2007; 14(6): 590-594.
5. Sperti C, Pasquali C, Berselli M, Frison L, Vicario G, Pedrazzoli S. Metastasis to the pancreas from colorectal cancer: is there a place for pancreatic resection? Diseases of the colon & rectum. 2009; 52(6): 1154-1159.
6. Sohn TA, Yeo CJ, Cameron JL, Nakeeb A, Lillemoe KD. Renal cell carcinoma metastatic to the pancreas: results of surgical management. Journal of Gastrointestinal Surgery. 2001; 5(4): 346-351.
7. Wente MN, Bergmann F, Fröhlich BE, Schirmacher P, Büchler MW, Friess H. Pancreatic metastasis from gastric carcinoma: a case report. World Journal of Surgical Oncology. 2004; 2(1): 1-4.
8. Sweeney AD, Wu M-F, Hilsenbeck SG, Brunicardi FC, Fisher WE. Value of pancreatic resection for cancer metastatic to the pancreas. Journal of Surgical Research. 2009; 156(2): 189-198.
9. Reddy S, Wolfgang CL. The role of surgery in the management of isolated metastases to the pancreas. The lancet oncology. 2009; 10(3): 287-293.
10. Song S-W, Cheng J-F, Liu N, Zhao T-H. Diagnosis and treatment of pancreatic metastases in 22 patients: a retrospective study. World Journal of Surgical Oncology. 2014; 12(1): 1-6.
11. Sperti C, Pasquali C, Chierichetti F, Ferronato A, Decet G, Pedrazzoli S. 18-Fluorodeoxyglucose positron emission tomography in predicting survival of patients with pancreatic carcinoma. Journal of Gastrointestinal Surgery. 2003; 7: 953-960.
12. Torres-Villalobos G, Podgaetz E, Anthon FJ, Remes-Troche JM, Robles-Diaz G, Nuñez CC. Single pancreatic metastasis from a previously resected carcinoma of the cecum: a case report. Current surgery. 2004; 61(3): 328-330.
13. Pereira-Lima J, Coral G, Bayer L, da Silva C. Metastasis from colon carcinoma in the dorsal pancreas of a patient with pancreas divisum: report of a case. Hepato-gastroenterology. 2000; 47(32): 554-555.
14. Schauer M, Vogelsang H, Siewert JR. Pancreatic resection for metastatic renal cell carcinoma: a single center experience and review of the literature. Anticancer research. 2008; 28(1B): 361-365.
15. Machado NO, Chopra P. Pancreatic metastasis from renal carcinoma managed by Whipple resection. A case report and literature review of metastatic pattern, surgical management and outcome. Jop. 2009; 10(4): 413-418.
16. Moussa A, Mitry E, Hammel P, et al. Pancreatic metastases: a multicentric study of 22 patients. Gastroenterologie clinique et biologique. 2004; 28(10): 872-876.
17. Chu P, Wu E, Weiss LM. Cytokeratin 7 and cytokeratin 20 expression in epithelial neoplasms: a survey of 435 cases. Modern Pathology. 2000; 13(9): 962-972.
18. Stoltz A, Barnoud R, Plok V, Ducerf C, Baulieux J, Mabrut J-Y. A pancreatic metastasis from a colon cancer. Clinics and research in hepatology and gastroenterology. 2011; 35(8-9): 586-589.
19. Bechade D, Palazzo L, Desrame J, et al. Métastases pancréatiques du cancer du rein: à propos de trois observations Pancreatic metastasis of renal cell carcinoma: report of three cases. La revue de médecine interne. 2002; 23: 862-866.
20. Bassi C, Butturini G, Falconi M, Sargenti M, Mantovani W, Pederzoli P. High recurrence rate after atypical resection for pancreatic metastases from renal cell carcinoma. Journal of British Surgery. 2003; 90(5): 555-559.
21. Varker KA, Muscarella P, Wall K, Ellison C, Bloomston M. Pancreatectomy for non-pancreatic malignancies results in improved survival after R0 resection. World Journal of Surgical Oncology. 2007; 5(1): 1-6.