17. Ứng dụng chất tiết tế bào gốc trung mô trong da liễu thẩm mỹ
Nội dung chính của bài viết
Tóm tắt
Lão hóa là một quá trình sinh học tất yếu ở mọi sinh vật sống. Trong những năm gần đây, các phương pháp chống lão hóa đã nhanh chóng phát triển để đáp ứng nhu cầu làm đẹp, tế bào gốc và các dẫn xuất của chúng đã trở thành một xu hướng tiềm năng trong lĩnh vực này. Tế bào gốc tiết ra các yếu tố tăng trưởng, cytokine, chemokine, yếu tố tạo mạch, peptide kháng khuẩn... đã được chứng minh là có tác động tích cực đến quá trình lão hóa da. Trong bài đánh giá này, chúng tôi tóm tắt cơ chế của các chất tiết từ tế bào gốc trong việc ngăn ngừa lão hóa da, phân lập và nuôi cấy tế bào gốc trung mô cũng như các quy trình chuẩn bị chất tiết. Ngoài ra, chúng tôi đề cập đến hiệu quả, hệ thống phân phối, khuyến nghị và triển vọng của các sản phẩm có nguồn gốc từ tế bào gốc. Tóm lại, so với các phương pháp điều trị chống lão hóa hiện có khác, chất tiết tế bào gốc có hiệu quả và tiềm năng vượt trội hơn. Tuy nhiên, việc sử dụng rộng rãi các sản phẩm này chưa được khuyến khích do thiếu các thử nghiệm lâm sàng trên người về tính an toàn và ổn định của chúng.
Chi tiết bài viết
Từ khóa
Tế bào gốc trung mô, chất tiết tế bào gốc, tái tạo da, trẻ hoá da, chế phẩm tế bào gốc
Tài liệu tham khảo
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3. Kim W, Park E, Yoo H S, et al. Recent advances in monitoring stem cell status and differentiation using nano-biosensing technologies. Nanomaterials. 2022;12(17):2934.
4. Vojnits K, Li Y. The current knowledge of immune privilege in stem cells. J Transplant Stem Cel Biol. 2014;1(1):4.
5. Hoang D M, Pham P T, Bach T Q, et al. Stem cell-based therapy for human diseases. Signal transduction and targeted therapy. 2022;7(1):1-41.
6. Ullah I, Subbarao R B, Rho G J. Human mesenchymal stem cells-current trends and future prospective. Bioscience reports. 2015;35(2):e00191.
7. Horwitz E M, Le Blanc K, Dominici M, et al. Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement. Cytotherapy. 2005;7(5):393-395.doi: 10.1080/14653240500319234.
8. Vagaska B, New S E P, Alvarez-Gonzalez C, et al. MHC-class-II are expressed in a subpopulation of human neural stem cells in vitro in an IFNγ–independent fashion and during development. Scientific reports. 2016;6(1):24251.
9. Machado C D V, Telles P D D S, Nascimento I L O. Immunological characteristics of mesenchymal stem cells. Revista brasileira de hematologia e hemoterapia. 2013;35:62-67.
10. Franquesa M, Herrero E, Torras J, et al. Mesenchymal stem cell therapy prevents interstitial fibrosis and tubular atrophy in a rat kidney allograft model. Stem cells and development. 2012;21(17):3125-3135.
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12. Prianishnikov V A. On the concept of stem cell and a model of functional-morphological structure of the endometrium. Contraception. 1978;18(3):213-223.
13. Gronthos S, Mankani M, Brahim J, et al. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proceedings of the National Academy of Sciences. 2000;97(25):13625-13630. doi: 10.1073/pnas.240309797.
14. Qu-Petersen Z, Deasy B, Jankowski R, et al. Identification of a novel population of muscle stem cells in mice: potential for muscle regeneration. The Journal of cell biology. 2002;157(5):851-864. doi: 10.1083/jcb.200108150.
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