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Đã xuất bản: 2025-05-30
Số lượt xem tóm tắt: 23
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DOI: https://doi.org/10.52852/tcncyh.v190i5E16.3069
Số xuất bản
Tập 190 Số 5E16 (2025)
Chuyên mục
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Cách trích dẫn
Deok-Chun, Y. ., Van Anh, P. T. ., Young Mi, C. ., Jeong Eun, K. ., Thuy, N. T. ., Se Chan, K. ., Byoung Man, K. ., Sung Keun, C. ., An, H. V. ., Thang, D. H. ., Thao, B. T. H. ., Hang, D. T. T. ., Mai, D. T. N. ., Hien, D. T. T. ., & Thanh, M. P. . (2025). A 90-day toxicological assessment of KRG hard capsules containing a water extract of Korean red ginseng in Wistar rats. Tạp Chí Nghiên cứu Y học, 190(5E16), 159-168. https://doi.org/10.52852/tcncyh.v190i5E16.3069

A 90-day toxicological assessment of KRG hard capsules containing a water extract of Korean red ginseng in Wistar rats

Yang Deok-Chun, Pham Thi Van Anh, Cho Young Mi, Kwon Jeong Eun, Nguyen Thi Thuy, Kang Se Chan, Kong Byoung Man, Choi Sung Keun, Hoang Van An, Doan Ha Thang, Bui Thi Huong Thao, Dinh Thi Thu Hang, Dang Thi Ngoc Mai, Dang Thi Thu Hien, Mai Phuong Thanh

Nội dung chính của bài viết

Tóm tắt

The KRG hard capsule was produced by Daedong Korea Ginseng Co. Ltd., with Korean red ginseng (Panax ginseng C. A. Meyer) as its primary component. This study aimed to assess the toxicity of KRG following 90 days of repeated oral dosing. Male and female Wistar rats received the test capsule orally once daily at 120 and 360 mg/kg/day over 90 days. The Korean red ginseng extract administration did not lead to any significant toxicological effects regarding mortality, body weight, hematological parameters, serum biochemistry, gross pathological observations, or histopathological analysis. Consequently, based on this toxicological evaluation, the KRG hard capsules are considered safe and non-toxic. The findings may serve as adequate preclinical evidence to support the initiation of future clinical trials involving KRG.

Chi tiết bài viết

Từ khóa

Korean red ginseng, toxicity, ginseng, rat

Tài liệu tham khảo

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