Evaluation of antitussive and expectorant activities of “Cam cum Ba giang” hard capsules in the experiment

Tóm tắt

The study aimed to evaluate the antitussive and expectorant activities of “Cam cum Ba giang” hard capsules. The antitussive effect of “Cam cum Ba giang” hard capsules was assessed using a murine model of ammonia-induced cough. The expectorant effect of “Cam cum Ba giang” hard capsules was evaluated by measuring tracheal phenol red output in mice. The results showed that “Cam cum Ba giang” hard capsules at 355.2 mg dried extract/kg/day and 710.4 mg dried extract/kg/day significantly inhibited cough and cough frequency and increased the latent period of cough. Moreover, “Cam cum Ba giang” hard capsules at both doses tended to pose the expectorant effect by slightly increasing the mice’s tracheal phenol red output compared to the control group. In conclusion, “Cam cum Ba giang” hard capsules, derived from herbal medicine, expressed antitussive and expectorant effects in experimental mice. Therefore, “Cam cum Ba giang” hard capsules may be a potential product for supporting the treatment of symptoms related to respiratory diseases in clinical settings.