Trends in breast cancer incidence among females in Hanoi, 2014-2023, and projections to 2040

Nguyen Huong Giang, Luu Minh Ngoc, Tran Thi Thanh Huong

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Tóm tắt

Breast cancer is the most common cancer among women worldwide and in Vietnam. This study aimed to describe trends in breast cancer incidence among females in Hanoi from 2014 to 2023 and to project the future burden up to 2040. A cross-sectional study with temporal trend analysis was conducted using data from the Hanoi Cancer Registry. Incident cases (ICD-10 code C50) diagnosed between January 1, 2014, and December 31, 2023, were included. Trends were analyzed using Joinpoint regression (version 5.0.2, National Cancer Institute, USA), with a jump model applied to account for potential disruptions during the COVID-19 period. Future cases were projected using a Poisson regression model with population as an offset in Stata version 17.0. A total of 15,646 cases were recorded, with an overall age-standardized incidence rate of 37.77 per 100,000 women. Incidence remained stable from 2014 to 2018, followed by a significant increase from 2018 to 2023. Projections indicate that cases may rise from 1,972 in 2023 to approximately 3,325 by 2040, particularly among women aged ≥50 years old, highlighting the urgent need to strengthen targeted early detection and mammography screening programs for this population.

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Tài liệu tham khảo

1. Bray F, Laversanne M, Sung H, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians. 2024; 74(3): 229-263. doi:10.3322/caac.21834.
2. Gu H, Wang R, Beeraka N, et al. Global burden and trends of breast cancer: GLOBOCAN 2022 estimates of incidence and mortality in 185 countries. Chinese Medical Journal. 2026; 139(3): 404-414. doi:10.1097/CM9.0000000000003921.
3. Bray F, Znaor A, Cueva P, Korir A, Swaminathan R, Ullrich A, Wang SA, Parkin DM. Planning and Developing Population-Based Cancer Registration in Low- and Middle-Income Settings. IARC; 2014. IARC Technical Publication No. 43.
4. Le Van Quang, Pham Xuan Dung, Tran Van Thuan, et al. Population-Based Cancer Registry in Hanoi and Ho Chi Minh City. National Cancer Hospital; 2023. Accessed March 17, 2026.
5. Pham DX, Ho TH, Bui TD, Ho-Pham LT, Nguyen TV. Trends in breast cancer incidence in Ho Chi Minh City 1996-2015: A registry-based study. PLoS One. 2021; 16(2): e0246800. Published 2021 Feb 10. doi:10.1371/journal.pone.0246800.
6. Nguyen SM, Deppen S, Nguyen GH, Pham DX, Bui TD, Tran TV. Projecting cancer incidence for 2025 in the 2 largest populated cities in Vietnam. Cancer control. 2019; 26(1)doi.:1073274819865274.
7. Ahmad OB, Boschi-Pinto C, Lopez AD, Murray CJ, Lozano R, Inoue M. Age Standardization of Rates: A new WHO Standard. GPE Discussion Paper Series, No. 31. 2001. Geneva: World Health Organization.
8. Youn HJ, Han W. A Review of the Epidemiology of Breast Cancer in Asia: Focus on Risk Factors. Asian Pac J Cancer Prev. 2020; 21(4): 867-880. doi:10.31557/APJCP.2020.21.4.867.
9. Cheng Y, Yan Y, Gong J, Yang N, Nie S. Trends in incidence and mortality of female breast cancer during transition in Central China. Cancer Manag Res. 2018; 10: 6247-6255. Published 2018 Nov 23. doi:10.2147/CMAR.S182510.
10. Sangrajrang S, Laversanne M, Bausom R, Mery L, Bray F. Cancer incidence and cancer control in Bangkok, Thailand: Results from the cancer registry 2011-15 and projections to 2035. Cancer Epidemiology. Cancer Epidemiol. 2020; 67: 101765. doi:10.1016/j.canep.2020.101765.
11. Bleyer A. Welch HG: Effect of three decades of screening mammography on breast-cancer incidence. N Engl J Med. 2012; 367(21): 1998-2005. doi:10.1056/NEJMoa1206809.
12. Chotai N, Renganathan R, Uematsu T, et al. Breast Cancer Screening in Asian Countries: Epidemiology, Screening Practices, Outcomes, Challenges, and Future Directions. Korean J Radiol. 2025; 26(8): 743-758. doi:10.3348/kjr.2025.0338.
13. Łukasiewicz S, Czeczelewski M, Forma A, J B, R S, A S. Breast Cancer-Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies-An Updated Review. Cancers. 2021; 13(17). doi:10.3390/cancers13174287.