Efficacy and safety of Trang Phuc Linh Plus tablets in patients with irritable bowel syndrome-diarrhea

Pham Thi Van Anh, Nguyen Phuong Thanh, Dau Thuy Duong, Nguyen Thi Thuy, Dang Thi Ngoc Mai, Nguyen Duc Linh Chi, Nguyen Quang Thai, Hoang Xuan Ba, Hoang Thi Huong, Tran Ngoc Anh, Duong Cong Thanh, Nguyen Thi Phuong Anh

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Tóm tắt

A double-blind, randomized, phase II clinical trial was conducted within a 14-week follow-up including 2 weeks of the non-drug run-in period, 8 weeks of medication, and 4 weeks of follow-up after discontinuation. The objective of the study was to evaluate the efficacy and safety of Trang Phuc Linh Plus in irritable diarrhea syndrome patients. Group I took Trang Phuc Linh Plus 3 tablets/time x 2 times/day for 8 weeks; Group II took placebo 3 tablets/time x 2 times/day for 8 weeks. Patients will be re-examined, tested, and evaluated over the phone for symptom recurrence and adverse events (AEs). This study showed that the Trang Phuc Linh Plus tablets tended to improve symptoms in patients suffering from irritable bowel syndrome with diarrhea, suggesting its safety and tolerability.

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Tài liệu tham khảo

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