5. Prevalence and its associated factors of extracranial carotid stenosis in patients with transient ischemic or ischemic stroke in Bach Mai Hospital

Bui Nguyen Tung, Mai Duy Ton, Pham Manh Hung

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Tóm tắt

Incidence of transient ischemic attack (TIA) or ischemic stroke has increased in recent years in Viet Nam due to lifestyle changes. Carotid stenosis is a common cause of TIA/ischemic stroke. The purpose of this study was to estimate current prevalence and identify risk factors of ipsilateral internal carotid artery (ICA) stenosis in patients with TIA/ischemic stroke. We recruited patients hospitalized to Bach Mai hospital in the first half of 2021 who suffered from TIA/ischemic stroke. The primary outcome is the presence of significant carotid stenosis, defined as atherosclerotic narrowing of 50 percent or greater, and confirmed by multidisciplinary team (MDT) discussion. In total, 328 consecutive patients with TIA/ischemic stroke were included in this study. Of these, 29 (8.84%, 95% confidence interval (CI): 6.0 -12.45) have 50-99% ipsilateral ICA stenosis. Patients with considerable ICA stenosis are more likely to have type 2 diabetes, ischemic heart disease (IHD) and higher creatinine serum level. On multivariate logistic regression, type 2 diabetes (OR 2.61; CI 95%: 1.14 -5.97, p = 0,034), IHD (OR 5.27; CI 95%: 1.68 - 16.56, p < 0.001), creatinine level (OR 1.15/10 mmol/l ; CI 95%: 1.01 -1.3, p = 0.031) are statistically significant risk factors for 50-99% ICA stenosis. The prevalence of extracranial ICA stenosis in TIA/ischemic stroke patient in Viet Nam is lower than Western countries but quite similar to Asia regions. Diabetes mellitus, IHD and high creatinine level are important risk factors for symptomatic ICA stenosis.

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Tài liệu tham khảo

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