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Published: 2022-03-01
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DOI: https://doi.org/10.52852/tcncyh.v151i3.631
Issue
Vol. 151 No. 3 (2022)
Section
Các bài báo
How to Cite
Long, D. H. ., & Hùng, H. S. . (2022). A comparison of hCG trigger versus dual trigger for final oocyte maturation in poor ovarian responders. Journal of Medical Research, 151(3), 162-169. https://doi.org/10.52852/tcncyh.v151i3.631

A comparison of hCG trigger versus dual trigger for final oocyte maturation in poor ovarian responders

Duong Hoang Long, Ho Sy Hung

Main Article Content

Abstract

This study compared the final oocyte maturation and the embryo formation between two groups,
one group in which follicular maturation was triggered by hCG alone versus the other group
triggered by a combination of hCG and GnRHa. This study was conducted at National Hospital of
Obstetric and Gynaecology. Patients who were poor ovarian responders as defined by the Bologna
criteria were randomized into two groups: the control group received the hCG trigger (10000IU)
and the investigation group received the dual trigger (0.2mg of Triptoreline plus 6500IU of hCG).
The number of retrieved oocytes, number of mature oocytes (MII), number of embryos formation
were all significantly higher in the investigation group compared to control group (p < 0.05). The
fertilization rate and the number of top embryos were not significantly different between the two
groups. Dual trigger for final oocyte maturation can improve IVF outcome in poor ovarian responders.

Article Details

Keywords

oocyte maturation, hCG trigger, dual trigger, poor ovarian responder

References

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