Co - infections in children with severe community-acquired pneumonia

Trần Quang Khải, Nguyễn Thị Diệu Thúy, Trần Đỗ Hùng, Phạm Hùng Vân

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Abstract

Pneumonia is one of the leading causes of death in children under 5 years old. Historically, viruses have been the most co mmon cause of co mmunity - acquired pneumonia in children. Co - infections in severe pneumonia are of concern by physicians. Real - time PCR is a modern test to detect many pathogens, including co - infections. Therefore, we applied this technique to investigate the causes of severe pneumonia. Through the analysis of 95 samples, there were 90.5% of PCR positive. Virus - bacteria co - infection accounted in highest proportion (43.1%), followed by bacterial - bacterial co - infection (33.7%), virus infection was 7.4% and bacterial causes was 6.3% with 9.5% causes was unknown. In the co - infection group, the following five bacterial species were co mmonly involved, in descending order including Streptococcus pneumoniae, Haemophilus influenzae, MRSA, Moraxella catarrhalis and Mycoplasma pneumoniae. As a result, antibiotic treatment should focus on these microbes in cases of severe pneumonia.

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References

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