Đặc điểm lâm sàng, hóa sinh và một số nguyên nhân hạ canxi máu nặng ở trẻ bú mẹ

Abstract

Severe hypocalcemia is  often considered an emergency, and if not diagnosed and treated promptly, may lead to death. However, hypocalcaemia is a preventable condition. We described clinical and biochemical characteristics and identified causes of severe hypocalcaemia among children age 0 to 12 months. This case series study included 69 children aged 0 to 12 months who were diagnosed with severe hypocalcaemia and received inpatient treatment at the National Children’s Hospital from January, 2018 to September,2019. Common clinical symptoms included convulsions (95.7%), irritation-crying (63.8%), refusal to breastfeed (21.7%), wheezing (18.8%), and lethargy (7.3%). Two out of 69 patients presented with cardiogenic shock. Plasma cancium levels were low. The most common cause of hypocalcemia was vitamin D deficiency (86.9%). Clinical symptoms of hypocalcemia in infants were not specific. Prophylactic vitamin D supplementation should be administered to nursing infants in order to prevent severe hypocalcemia.