Hemorrhagic bullous lesions in a child with henoch schönlein purpura
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Abstract
The characteristic skin lesions of Henoch-Schˆnlein purpura (HSP) are non-thrombocytopenic palpable purpura of the lower extremities and buttocks which can be fully recovered without specific treatment. Hemorrhagic bullae is a rare cutaneous manifestation in children with HSP, making it difficult to diagnose and may lead to skin sequelae. We reported a 9-year-old boy with palpable purpura of both legs and arthritis. He was diagnosed with HSP and treated with ibuprofen. After 8 days of treatment, the skin lesions rapidly changed into hemorrhagic bullous lesions. A histological examination of a skin biopsy showed signs of leukocytoclastic vasculitis and direct immunofluorescence analysis revealed IgA, C3c deposits in vessel walls. Patient was treated with systemic corticosteroids tapered over 45 days; subsequently, his skin lesions showed complete remission but maitaining scarring in some affected areas. Hemorrhagic bullous lesions are rare in HSP but may lead to skin sequelae, when combined with histopathology will lead to an accurate diagnosis and appropriate treatment.
Article Details
Keywords
Henoch-Schönlein purpura, hemorrhagic bullae, children
References
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