Clinical symptoms, endoscopic findings and high resolution manometryc results in patients with distal esophageal spasm

Đào Việt Hằng, Lưu Thị Minh Huế

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Abstract

A retrospective study was conducted to describe clinical symptoms, endoscopic findings, and high-resolution manometry (HRM) results in patients with distal esophageal spasm (DES). There were 75 of 7519 patients diagnosed of DES on HRM between 3/2018 to 8/2020 at the Institute of Gastroenterology and Hepatology. The study sample included 62.7% women, the mean age was 47.8 years. The prevalence of dysphagia and chest pain were 41.3% and 30.7%, respectively. Other common symptoms included regurgitation (72.0%), belching (56.0%), and heartburn (49.3%). 46.8% of patients had erosive esophagitis on endoscopy. On HRM, the median percentage of premature swallows was 30%. Patients with dysphagia with or without chest pain had significantly higher 4-second integrated relaxation pressure (IRP4s) than those without these symptoms. There was no correlation between dysphagia or chest pain and the percentage of premature contraction.

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References

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