24. Đặc điểm dịch tễ học lâm sàng và căn nguyên ở bệnh nhân nghi ho gà tại Bệnh viện Bệnh Nhiệt đới Trung ương

Abstract

Whooping cough is an acute infectious disease that spreads through the respiratory tract and affects people of all ages, most notably children under the age of five. The incubation period ranges from 2 to 30 days, and the disease progresses through various stages, with common complications including bronchopneumonia, cough, intussusception, rectal prolapse, encephalitis... Although vaccines are available, morbidity and complications remain high. The aim of the study is to describe the clinical epidemiological characteristics and etiological distribution of whooping cough in Vietnam. Bordetella pertussis was found in 19% of the patients, with 86.6% being under one year old and a male/female ratio of 1.9/1. Clinical symptoms include a persistent cough, pancreatitis, vomiting, and regurgitation, with a mean hospital admission of 13.6 days. Bronchopneumonia, pneumonia, eyelid edema, and superinfection are among the complications; in the unvaccinated group, the incidence reached 63.4%. There were patients infected with the disease in a year, with the highest number occurring between March and June. Even though there is a vaccine to prevent pertussis, the disease continues to spread. Patients have typical clinical manifestations and numerous complications.