Depression among patients with methadone and buprenorphine maintenance treatment in the northern mountainous areas of vietnam: prevalence and related factors

Phạm Thành Luân, Vũ Minh Anh, Nguyễn Bích Diệp, Nguyễn Thu Trang, Nguyễn Thị Minh Tâm, Hoàng Đình Cảnh, Lê Minh Giang

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Abstract

Studies have shown that depression is the most common psychiatric comorbidity in drug-dependent patients in opioid substitution treatment. The objective of this study was to investigate the prevalence of depression and related factors for depression in drug-dependent patients in methadone and buprenorphine maintenance treatment. We performed a descriptive cross-sectional study in 3 methadone maintenance therapy (MMT) service units from the northern mountainous provinces of Vietnam on 344 patients enrolling in treatment from March to December 2019. The PHQ-2 depression screening scale were used to assess depression among patients. Results: The prevalence of depression (PHQ- 2 ≥ 2) overall was 7,3%, of which methadone patients represent 1,7% and buprenorphine patients 10,2%, (p <0,05). Risk factors for depression were buprenorphine maintenance treatment (p = 0,019). Research has shown a relative prevalence  of depression in opioid addiction treatment patients, suggesting the need for appropriate supportive services to improve the effectiveness of the opioid substitution program in Vietnam.

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References

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