11. Immune cell characterisrtics of peripheral blood in patients with nasopharygeal carcinoma
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Abstract
A cross-sectional study on 44 patients with nasopharyngeal carcinoma (NPC) diagnosed by histopathology and 46 healthy people of same-sex and age to evaluate the cell count of T lymphocyte and subset, B lymphocyte and NK cell of peripheral blood in patients with nasopharyngeal carcinoma. The result showed that, the ratio between males and females is 2:1, the everage age of NPC paptient is 51.52 ± 1.78 year-old and 65.9% of the patients are diagnosed in late stages III - IV. Cell count of T lymphocyte, TCD4 lymphocyte, TCD8 lymphocyte and B lymphocyte 1188.91 ± 277.76 cells/µl; 629.05 ± 195.74 cells/µl/ µl; 488.73 ± 165.02 cells/µl/ µl and 213.23 ± 98.05 are significant lower than those of healthy control people 1479.30 ± 425.24 cells/µl/ µl; 735.01 ± 237.70 cells/µl; 634.15 ± 243.35 cells/µl and 283.88 ± 131.95, respectively with p < 0.05. The ratio of TCD4/TCD8 is no significant difference between NPC patients and healthy control people with p = 0,224. NK cell count of NPC patients is increase compare to that in healthy control people, however is not significant difference with p = 0.417. Cell count of T, TCD4, TCD8, B lymphocytes and NK cell are no significant difference between early (I + II) and late (III + IV) satges of NPC paptients.
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Keywords
Nasopharyngeal carcinoma, T Lymphocyte, B lymphocyte, NK cell
References
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