12. Current status of using anti - inflammatory treatment in patients with rheumatoid arthritis using biological drugs

Dao Thi Yen, Bui Hai Binh, Hoang Thi Hai Van

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Abstract

This study aims to explore the presence of using anti-inflammatory drugs in patients with rheumatoid arthritis using biological drugs at the Centre for Rheumatology, Bach Mai Hospital. The cross-sectional descriptive study included 153 patients diagnosed with rheumatoid arthritis using biological drugs at the Centre for Rheumatology, Bach Mai Hospital in the period from August 2019 to August 2022. The results revealed that 81% of patients took anti-inflammatory drugs, of which glucocorticoid (GC) accounts for 79%, and non-steroidal anti-inflamatory drugs (NSAIDs) were 21%. The dose of GC calculated according to methylprednisolone was mainly low dose, accounting for 97%, the most used dose was 4mg, accounting for 79.7%. With NSAIDs, the COX-2 inhibitors were used more at 65.3%, celecoxib accounts for the highest proportion at 61.5%. This study showed that the majority of patients using biologic therapy continued to take anti-inflammatory drugs, with a higher prevalence of GC than NSAIDs. Patients receive GC mainly at low doses. COX-2selective inhibitors are more commonly used.

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References

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