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Published: 2023-03-31
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DOI: https://doi.org/10.52852/tcncyh.v164i3.1479
Issue
Vol. 164 No. 3 (2023)
Section
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Lượng V. Đình . (2023). 20. Comparing the effects of levobupivacain and bupivacain on spinal anesthesia for caesarean section at Thai Binh Maternity Hospital in 2021. Journal of Medical Research, 164(3), 161-169. https://doi.org/10.52852/tcncyh.v164i3.1479

20. Comparing the effects of levobupivacain and bupivacain on spinal anesthesia for caesarean section at Thai Binh Maternity Hospital in 2021

Vu Dinh Luong

Main Article Content

Abstract

Random clinic trials and controlled single-blind study was conducted to compare the effects of levobupivacain and bupivacain on spinal anesthesia for cesarean section. 120 pregnant women are randomly divided into 2 groups, group B and group L, receiving 8mg bupivacaine combined with 30mcg fentanyl and 8mg levobupivacaine combined with 30mcg fentanyl respectively. The effects of sensory inhibition, motor inhibition, hemodynamic stability and undesirable effects (if any) were studied. The duration of time to reach skin sensation block to T6 in group B was 3.87 ± 1.17 minutes compared with group L 4.53 ± 2.05 minutes. The duration of time to reach motor block M1 level in group B was 2.83 ± 1.12 minutes compared to group L 5.33 ± 1.35 minutes. Pain relief time was prolonged in group B (304.77 ± 17.47 minutes) compared with group L (262.43 ± 47.01 minutes) (p < 0.05). The hemodynamic stability of group B was less than group L with the presence of the decreased blood pressure. This study showed that 8mg of levobupivacaine plus 30mcg of fentanyl in spinal anesthesia for cesarean section had a sensory and motor block effect comparable to 8mg of bupivacaine plus fentanyl, with a longer duration of onset with little effect on to hemodynamics.

Article Details

Keywords

Bupivacaine, levobupivacaine, caesarean section, spinal anaesthesia

References

1. Louis A, Tiwary M K, Sharma P, Nair A S. Comparison of Postoperative Pulmonary Outcomes in Patients Undergoing Cesarean Section under General and Spinal Anesthesia: A Single-Center Audit. Anesth Essays Res. 2021;15(4):439-442. doi: 10.4103/aer.aer_6_22.
2. Turkmen A, Moralar D G, Ali A, et al. Comparison of the anesthetic effects of intrathecal levobupivacaine + fentanyl and bupivacaine + fentanyl during caesarean section. Middle East J Anaesthesiol. 2012;21(4):577-582.
3. Bowring J, Fraser N, Vause S, Heazell A E. Is regional anaesthesia better than general anaesthesia for caesarean section? J Obstet Gynaecol. 2006;26(5):433-434. doi: 10.1080/01443610600720345.
4. Bremerich D H, Fetsch N, Zwissler B C, et al. Comparison of intrathecal bupivacaine and levobupivacaine combined with opioids for Caesarean section. Curr Med Res Opin. 2007;23(12):3047-3054. doi: 10.1185/030079907X242764.
5. Gautier P, De Kock M, Huberty L, et al. Comparison of the effects of intrathecal ropivacaine, levobupivacaine, and bupivacaine for Caesarean section. Br J Anaesth. 2003;91(5):684-689. doi: 10.1093/bja/aeg251.
6. Gori F, Corradetti F, Cerotto V, et al. Influence of positioning on plain levobupivacaine spinal anesthesia in cesarean section. Anesthesiol Res Pract. 2010;2010. doi: 10.1155/2010/212696.
7. Phạm Đông An, Chừng Nguyễn Văn. Nghiên cứu hiệu quả của gây tê tủy sống bằng hỗn hợp Bupivacaine và Fentanyl trong mổ lấy thai. Tạp chí Y học thực hành Thành phố Hồ Chí Minh. 2004;1(9):51-57.
8. Trần Ngọc San. So sánh gây tê tủy sống bằng levobupivacain kết hợp fentanyl với bupivacain kết hợp fentanyl trong phẫu thuật lấy thai. Tạp chí Y học thực hành. 2014.