13. Initial results of progestin-primed ovarian stimulation in andrology and fertility Hospital of Hanoi

Nguyen Thanhh Trung, Le Thi Thu Hien, Ho Van Thang, Pham Thi My Hanh, Nguyen Thi Huyen Trang

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Abstract

The study aimed to to describe the pregnancy outcome of progestin-primed ovarian stimulation (PPOS) in the Andrology and Fertility Hospital Of Hanoi. This was a retrospective cohort study,  included 89 patients undergoing controlled ovarian stimulation with PPOS protocol during May 2022 to August 2022. The results showed that LH on trigger day was 4.15 ± 2.72 mIU/ml; E2 on trigger day was 5652.16 ± 3135.80 pg/mL; P4 on trigger day was 3.79 ± 2.04 (ng/mL). None of the patients ovulated prematurely and overstimulated the ovaries. M2 oocyte rate was 76.1%; fertilization rate was 87.8%. The rate of embryos on day 3 was 98.0%, the rate of good embryos was 41.6%. The rate of embryos on day 5 was 30.1%, the rate of good embryos on day 5 was 10.1%. There were 87 cases of embryo transfer, the beta-HCG positive rate was 86.2%; implantation rate was 72.7%; clinical pregnancy rate was 80.0%. Initial evaluation shows positive clinical outcomes  with the PPOS protocol. We suggest that additional prospective randomized trials should be conducted to assess the efficacy of PPOS protocols for early LH suppression.

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References

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