7. The effectiveness of mifepristone combined with misoprostol onabortion of from 13 to 22 weeks of gestation at the National hospital of obstetrics and gynecology

Vu Van Du, Pham Thi Yen, Le Thi Ngoc Huong

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Abstract

Regimen of the second-trimester abortion following National Manual Handbook, published in 2016, has not been researched. Our objective isto evaluate the effect of Mifepristone and Misoprostol on the second-trimeter abortion between 2 groups of 13 - 18 weeks and 19 - 22 weeks gestation. Methodology: this is a cross-sectional descriptive study at the National Hospital of Obstetrics and Gynecology among 130 gravidas with gestational age from 13 to 22 weeks, who underwent a medical abortion. Results: The miscarriage rate is 99.23%, the miscarriage time is 7.7 ± 3.67 (hours), and the smaller the fetal age – the shorter the miscarriage time and the lower the dosage . The rate of uterine intervention after the natural third stage of labour is 16.28%, the most frequent complication is fever (26.15%). Conclusion: The combination of Mifepristone and Misoprostol is highly effective for medical abortion during the secondtrimeter.

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References

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