12. Characteristics of calcium-phosphorus metabolization disorder and growth retardation in children with end-stage renal disease

Luong Thi Phuong, Luu Thi Hang, Nguyen Ngoc Huy, Nguyen Thu Huong

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Abstract

Growth retardation is a significant complication in children with chronic kidney disease (CKD) and end-stage chronic kidney disease (ESRD). Children with ESRD have growth retardation due to poor nutrition, anemia, bone and mineral disorders, growth hormone deficiency, and steroid exposure. A descriptive study was conducted on 54 ESRD children undergoing renal replacement therapy (79.6% peritoneal dialysis and 20.4% hemodialysis) at the Vietnam National Children's Hospital (55.6% men). The youngest was 5 months old and the oldest was 16 years old. 81.5% were diagnosed with stunting according to WHO with height for age (HFA) below -2SD. 23 out of 54 children (42.6%) have severe stunting with an HFA below -3SD. The percentages of children with total hypocalcemia and vitamin D deficiency were 68.5% and 48.1%, respectively. 80.9% have hyperphosphatemia and 96.7% have increased PTH.. Increased serum PTH was associated with ESRD children with growth retardation (p < 0.05).

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References

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