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Published: 2023-06-20
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DOI: https://doi.org/10.52852/tcncyh.v167i6.1665
Issue
Vol. 167 No. 6 (2023)
Section
Các bài báo
How to Cite
Lộc, P. Q., Vân, H. T. H., Hương, Đặng T., Quang, N. N., & Giang, L. M. (2023). 33. SARS-CoV-2 Vaccine Breakthrough Infections in Bac Ninh Province, Vietnam, in 2021. Journal of Medical Research, 167(6), 283-295. https://doi.org/10.52852/tcncyh.v167i6.1665

33. SARS-CoV-2 Vaccine Breakthrough Infections in Bac Ninh Province, Vietnam, in 2021

Pham Quang Loc, Hoang Thi Hai Van, Dang Thi Huong, Nguyen Ngo Quang, Le Minh Giang

Main Article Content

Abstract

The study aims to report the prevalence of SARS-CoV-2 vaccine breakthrough infections in Bac Ninh province and evaluate factors associated with the breakthrough infection proportion. Exiting data, retrieved from the immunization management system and the case management system in Bac Ninh province in 2021, were systematically processed and merged. SARS-CoV-2 vaccine breakthrough infections was defined as people with positive RT-PCR result for SARS-CoV-2 before December 28, 2021 and successfully linked with vaccination data. COVID-19 vaccine was enumerated when the date of vaccination at least 14 days before the date of confirmation of SARS-CoV-2 infection. There were 302,407 people vaccinated in Que Vo and Tien Du in 2021; among the vaccinated, 1,324 were infected with SARS-CoV-2, accounting for 0.44% (95%CI: 0.41% - 0.46 %). Younger age, female, and prolonged interval between doses were associated with an increased risk of breakthrough infection. Two or more doses and heterologous doses were associated with a reduced risk of breakthrough infection. SARS-CoV-2 vaccine breakthrough infections was low. Any COVID-19 vaccines are associated with a reduced risk of the infection so it is recommended to maintain vaccination and to adjust the time between doses for optimal effectiveness.

Article Details

Keywords

COVID-19, vaccine, breakthrough infection

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