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Published: 2023-06-20
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DOI: https://doi.org/10.52852/tcncyh.v167i6.1667
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Vol. 167 No. 6 (2023)
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Các bài báo
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Công, M. T., Huyền, T. T., Lê, N. T., Ngọc, L. T. K., & Ly, Đào K. (2023). 39. Bronchiolitis obliterans as a long-term sequela of mycoplasma pneumoniae-induced-stevens johnson: A case report. Journal of Medical Research, 167(6), 356-363. https://doi.org/10.52852/tcncyh.v167i6.1667

39. Bronchiolitis obliterans as a long-term sequela of mycoplasma pneumoniae-induced-stevens johnson: A case report

Mai Thanh Cong, Thuc Thanh Huyen, Nguyen Thi Le, Le Thi Kim Ngoc, Dao Khanh Ly

Main Article Content

Abstract

Steven-Johnson syndrome (SJS) is an immune-mediated hypersensitivity reaction, mainly related to medications and infections. It is characterized by blisters and extensive necrosis of the skin and mucous membranes, acute and usually self-limiting. Bronchiolitis Obliterans (BO) is a rare respiratory complication of SJS which occurs after the acute phase. We report a case of a 32-month-old boy diagnosed with SJS due to Mycoplasma pneumoniae, presenting with fever, cough, blister, oral mucosal ulcer and conjunctivitis, positive Mycoplasma pneumoniae test (IgM > 1352 U/mL). Skin and mucosal  lesions improved after 2 weeks, but after 5 weeks, he  developped wheezing and dyspnea. HRCT showed mosaic pattern, bronchial wall thichkening and air trapping. BO is a late respiratory complication of SJS. Long-term monitoring of respiratory manifestations in SJS patients is essential to have prompt interventions, avoiding more serious lung damage.

Article Details

Keywords

Bronchiolitis obliterans, Stevens Johnson syndrome, Mycoplasma pneumoniae

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