The coexistence of autoimmune thyroid disease and systemic lupus erythematosus in children: 2 cases report
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Abstract
Autoimmune thyroid diseases (AITD) include Hashimoto’s thyroiditis and Basedow’s disease. Many studies shows that the incidence of AITD in patients with systemic lupus erythematosus (SLE) is higher than in the general population, but most of these studies are in adults. We report 2 cases of teenage girls with goiter. One child was diagnosed for Hashimoto’s thyroiditis (T3 2.49 nmol/L, FT4 12.28 pmol/L, TSH 8.51 mUI/L, anti-Tg 1417 U/mL, anti-TPO 455.7 U/mL, TRAb 0.3 U/L) and the other was diagnosed for Basedow’s disease (T3 2.83 nmol, FT4 17.16 pmol/L, TSH 0.005 mUI/L, anti-Tg 513 U/mL, anti-TPO 156 U/mL, TRAb 33.9 U/L) with the clinical features and thyroid-specific antibodies. Besides, both patients experienced thrombocytopenia and were diagnosed for SLE. When treated for both thyroid disease and SLE, the platelet count returned to normal. AITD associates with SLE although rare in children, but physician should be attentive to diagnose correctly and initiate treatment.
Article Details
Keywords
Autoimmune thyroid disease, Hashimoto's thyroiditis, Basedow's disease, systemic lupus erythematosus, children.
References
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