13. Malnutrition status and related factors in gastric cancer patients undergoing chemotherapy treatment at Ho Chi Minh City oncology hospital
Main Article Content
Abstract
Chemotherapy is one type of systemic treatment for cancer that causes side effects on eating and energy supply, leading to weight loss and malnutrition. Detecting malnutrition early in gastric cancer patients plays a critical role in implementing an effective nutritional regimen that can improve their nutritional status, prevent weight loss, and enhance their ability to withstand and respond to chemotherapy. The cross-sectional study was performed on 95 patients in Ho Chi Minh City Oncology Hospital from October 2021 to June 2022. According to the PG-SGA, MUAC, and BMI, the percentage of malnutrition are 69.5%, 33.7%, and 31.6%, respectively. There is a statistically significant connection between malnutrition rate by PG-SGA with age categories, cancer treatment methods, side effects of chemotherapy, and anemia.
Article Details
Keywords
Malnutrition, gastric cancer, chemotherapy, PG-SGA.
References
1. Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: A Cancer Journal for Clinicians. 2021; 71(3): 209-249. doi:10.3322/caac.21660.
2. Liu GF, Tang D, Li P, et al. S-1-based combination therapy vs S-1 monotherapy in advanced gastric cancer: A meta-analysis. World J Gastroenterol. 2014; 20(1): 310-318. doi:10.3748/wjg.v20.i1.310.
3. Orditura M, Galizia G, Sforza V, et al. Treatment of gastric cancer. World J Gastroenterol. 2014; 20(7): 1635-1649. doi:10.3748/wjg.v20.i7.1635.
4. Grant M, Kravits K. Symptoms and their impact on nutrition. Semin Oncol Nurs. 2000; 16(2): 113-121. doi:10.1053/on.2000.5738.
5. Rosania R, Chiapponi C, Malfertheiner P, Venerito M. Nutrition in Patients with Gastric Cancer: An Update. Gastrointest Tumors. 2016; 2(4): 178-187. doi:10.1159/000445188.
6. Gavazzi C, Colatruglio S, Sironi A, Mazzaferro V, Miceli R. Importance of early nutritional screening in patients with gastric cancer. Br J Nutr. 2011; 106(12): 1773-1778. doi:10.1017/S0007114511002509.
7. Arends J, Bachmann P, Baracos V, et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr. 2017; 36(1): 11-48. doi:10.1016/j.clnu.2016.07.015.
8. Le Thi V, Nguyen Van Q, La Van L. Nutrition status and some related factors in the patient with gastrointestinal cancer who have chemotherapy treatment in the Oncology Center, Thai Nguyen National Hospital. Tạp chí Y dược học Cần Thơ. (34): 54-60.
9. Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey (NHANES): Anthropometry Procedures Manual. CreateSpace Independent Publishing Platform; 2014.
10. Yonei Y, Miwa Y, Hibino S, et al. Japanese Anthropometric Reference Data - Special Emphasis on Bioelectrical Impedance Analysis of Muscle Mass. ANTI-AGING MEDICINE. 2008; 5: 63-72. doi:10.3793/jaam.5.63.
11. Bauer J, Capra S, Ferguson M. Use of the scored Patient-Generated Subjective Global Assessment (PG-SGA) as a nutrition assessment tool in patients with cancer. Eur J Clin Nutr. 2002; 56(8): 779-785. doi:10.1038/sj.ejcn.1601412.
12. World Health Organization. Nutritional anemia: report of a WHO Scientific Group. World Health Organ Tech Rep Ser. 1968; 405: 1-40.
13. Crew KD, Neugut AI. Epidemiology of gastric cancer. World J Gastroenterol. 2006; 12(3): 354-362. doi:10.3748/wjg.v12.i3.354.
14. Thuy NT, Hương LT, Thanh NT. Nutritional status of gastric cancer patients during chemotherapy at Cancer Hospital in 2020 - 2021. TCNCYH. 2021; 146(10): 140-149. doi:10.52852/tcncyh.v146i10.460.
15. Phuong DT, Huong LT, Linh NT, Yen DT. Nutritional status of cancer patients at HaNoi Medical University Hospital in 2016. TCNCYH. 2017; 106(1): 163-169. doi:10.52852/tcncyh.v146i10.460.
16. Gebremedhin TK, Cherie A, Tolera BD, Atinafu BT, Demelew TM. Prevalence and risk factors of malnutrition among adult cancer patients receiving chemotherapy treatment in cancer center, Ethiopia: cross-sectional study. Heliyon. 2021; 7(6): e07362. doi:10.1016/j.heliyon.2021.e07362.
17. Wu BW, Yin T, Cao WX, et al. Clinical application of subjective global assessment in Chinese patients with gastrointestinal cancer. World J Gastroenterol. 2009; 15(28): 3542-3549. doi:10.3748/wjg.15.3542.
18. Cho JW, Youn J, Kim EM, Choi MG, Lee JE. Associations of patient-generated subjective global assessment (PG-SGA) and NUTRISCORE with survival in gastric cancer patients: timing matters, a retrospective cohort study. BMC Gastroenterol. 2022; 22: 468. doi:10.1186/s12876-022-02515-3.
19. Zhang Q, Li XR, Zhang X, et al. PG-SGA SF in nutrition assessment and survival prediction for elderly patients with cancer. BMC Geriatr. 2021; 21: 687. doi:10.1186/s12877-021-02662-4.
20. Vranešić Bender D, Krznarić Ž. Nutritional issues and considerations in the elderly: an update. Croat Med J. 2020; 61(2): 180-183. doi:10.3325/cmj.2020.61.180.
21. Body composition changes with aging: The cause or the result of alterations in metabolic rate and macronutrient oxidation? - PMC. Accessed May 2, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880224/.
22. Pirlich M, Lochs H. Nutrition in the elderly. Best Practice & Research Clinical Gastroenterology. 2001; 15(6): 869-884. doi:10.1053/bega.2001.0246.
23. Miedziaszczyk M, Ciabach P, Szałek E. The Effects of Bariatric Surgery and Gastrectomy on the Absorption of Drugs, Vitamins, and Mineral Elements. Pharmaceutics. 2021; 13(12): 2111. doi:10.3390/pharmaceutics13122111.
24. Ukleja A. Dumping Syndrome: Pathophysiology and Treatment. Nutrition in Clinical Practice. 2005; 20(5): 517-525. doi:10.1177/0115426505020005517.
25. Hironaka S, Ueda S, Yasui H, et al. Randomized, open-label, phase III study comparing irinotecan with paclitaxel in patients with advanced gastric cancer without severe peritoneal metastasis after failure of prior combination chemotherapy using fluoropyrimidine plus platinum: WJOG 4007 trial. J Clin Oncol. 2013; 31(35): 4438-4444. doi:10.1200/jco.2012.48.5805.
26. Lim CH, Kim SW, Kim WC, et al. Anemia after gastrectomy for early gastric cancer: Long-term follow-up observational study. World J Gastroenterol. 2012; 18(42): 6114-6119. doi:10.3748/wjg.v18.i42.6114.
2. Liu GF, Tang D, Li P, et al. S-1-based combination therapy vs S-1 monotherapy in advanced gastric cancer: A meta-analysis. World J Gastroenterol. 2014; 20(1): 310-318. doi:10.3748/wjg.v20.i1.310.
3. Orditura M, Galizia G, Sforza V, et al. Treatment of gastric cancer. World J Gastroenterol. 2014; 20(7): 1635-1649. doi:10.3748/wjg.v20.i7.1635.
4. Grant M, Kravits K. Symptoms and their impact on nutrition. Semin Oncol Nurs. 2000; 16(2): 113-121. doi:10.1053/on.2000.5738.
5. Rosania R, Chiapponi C, Malfertheiner P, Venerito M. Nutrition in Patients with Gastric Cancer: An Update. Gastrointest Tumors. 2016; 2(4): 178-187. doi:10.1159/000445188.
6. Gavazzi C, Colatruglio S, Sironi A, Mazzaferro V, Miceli R. Importance of early nutritional screening in patients with gastric cancer. Br J Nutr. 2011; 106(12): 1773-1778. doi:10.1017/S0007114511002509.
7. Arends J, Bachmann P, Baracos V, et al. ESPEN guidelines on nutrition in cancer patients. Clin Nutr. 2017; 36(1): 11-48. doi:10.1016/j.clnu.2016.07.015.
8. Le Thi V, Nguyen Van Q, La Van L. Nutrition status and some related factors in the patient with gastrointestinal cancer who have chemotherapy treatment in the Oncology Center, Thai Nguyen National Hospital. Tạp chí Y dược học Cần Thơ. (34): 54-60.
9. Centers for Disease Control and Prevention. National Health and Nutrition Examination Survey (NHANES): Anthropometry Procedures Manual. CreateSpace Independent Publishing Platform; 2014.
10. Yonei Y, Miwa Y, Hibino S, et al. Japanese Anthropometric Reference Data - Special Emphasis on Bioelectrical Impedance Analysis of Muscle Mass. ANTI-AGING MEDICINE. 2008; 5: 63-72. doi:10.3793/jaam.5.63.
11. Bauer J, Capra S, Ferguson M. Use of the scored Patient-Generated Subjective Global Assessment (PG-SGA) as a nutrition assessment tool in patients with cancer. Eur J Clin Nutr. 2002; 56(8): 779-785. doi:10.1038/sj.ejcn.1601412.
12. World Health Organization. Nutritional anemia: report of a WHO Scientific Group. World Health Organ Tech Rep Ser. 1968; 405: 1-40.
13. Crew KD, Neugut AI. Epidemiology of gastric cancer. World J Gastroenterol. 2006; 12(3): 354-362. doi:10.3748/wjg.v12.i3.354.
14. Thuy NT, Hương LT, Thanh NT. Nutritional status of gastric cancer patients during chemotherapy at Cancer Hospital in 2020 - 2021. TCNCYH. 2021; 146(10): 140-149. doi:10.52852/tcncyh.v146i10.460.
15. Phuong DT, Huong LT, Linh NT, Yen DT. Nutritional status of cancer patients at HaNoi Medical University Hospital in 2016. TCNCYH. 2017; 106(1): 163-169. doi:10.52852/tcncyh.v146i10.460.
16. Gebremedhin TK, Cherie A, Tolera BD, Atinafu BT, Demelew TM. Prevalence and risk factors of malnutrition among adult cancer patients receiving chemotherapy treatment in cancer center, Ethiopia: cross-sectional study. Heliyon. 2021; 7(6): e07362. doi:10.1016/j.heliyon.2021.e07362.
17. Wu BW, Yin T, Cao WX, et al. Clinical application of subjective global assessment in Chinese patients with gastrointestinal cancer. World J Gastroenterol. 2009; 15(28): 3542-3549. doi:10.3748/wjg.15.3542.
18. Cho JW, Youn J, Kim EM, Choi MG, Lee JE. Associations of patient-generated subjective global assessment (PG-SGA) and NUTRISCORE with survival in gastric cancer patients: timing matters, a retrospective cohort study. BMC Gastroenterol. 2022; 22: 468. doi:10.1186/s12876-022-02515-3.
19. Zhang Q, Li XR, Zhang X, et al. PG-SGA SF in nutrition assessment and survival prediction for elderly patients with cancer. BMC Geriatr. 2021; 21: 687. doi:10.1186/s12877-021-02662-4.
20. Vranešić Bender D, Krznarić Ž. Nutritional issues and considerations in the elderly: an update. Croat Med J. 2020; 61(2): 180-183. doi:10.3325/cmj.2020.61.180.
21. Body composition changes with aging: The cause or the result of alterations in metabolic rate and macronutrient oxidation? - PMC. Accessed May 2, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880224/.
22. Pirlich M, Lochs H. Nutrition in the elderly. Best Practice & Research Clinical Gastroenterology. 2001; 15(6): 869-884. doi:10.1053/bega.2001.0246.
23. Miedziaszczyk M, Ciabach P, Szałek E. The Effects of Bariatric Surgery and Gastrectomy on the Absorption of Drugs, Vitamins, and Mineral Elements. Pharmaceutics. 2021; 13(12): 2111. doi:10.3390/pharmaceutics13122111.
24. Ukleja A. Dumping Syndrome: Pathophysiology and Treatment. Nutrition in Clinical Practice. 2005; 20(5): 517-525. doi:10.1177/0115426505020005517.
25. Hironaka S, Ueda S, Yasui H, et al. Randomized, open-label, phase III study comparing irinotecan with paclitaxel in patients with advanced gastric cancer without severe peritoneal metastasis after failure of prior combination chemotherapy using fluoropyrimidine plus platinum: WJOG 4007 trial. J Clin Oncol. 2013; 31(35): 4438-4444. doi:10.1200/jco.2012.48.5805.
26. Lim CH, Kim SW, Kim WC, et al. Anemia after gastrectomy for early gastric cancer: Long-term follow-up observational study. World J Gastroenterol. 2012; 18(42): 6114-6119. doi:10.3748/wjg.v18.i42.6114.