16. The outcome of obstructive sleep apnea treatment in children with tonsillar hypertrophy by leukotriene receptor antagoinists

Phi Thi Quynh Anh, Pham Duc Huy, Dao Hoa Phuong, Pham Dang Hoang Giang, Pham Thi Thu Huyen, Tran Minh Dien

Main Article Content

Abstract

The study evaluates the effectiveness of mild and moderate obstructive sleep apnea syndrome treatment in children with adenoid and tonsillar hypertrophy by leukotriene receptor antagoinists. A total of 63 children from 2 - 12 years old with tonsillar hypertrophy diagnosed with OSAS at the National Children's Hospital between August 2016 and December 2019 were included. The standard for diagnosis of OSAS in children is the apnea-hypopnea index (AHI) ≥ 1 measured by polysomnography during sleep, condition is considered as mild with AHI level between 1 to 5 (1 ≤ AHI < 5) and moderate as AHI level between 5 to 10 (5 ≤ AHI < 10). Results: After 3 months of treatment, there were improvements in the indicators on the sleep respiratory polygraph and all clinical symptom groups. Nearly 50% of children no longer have apnea according to AHI criteria < 1. Treatment with leukotriene receptor antagoinists improves both clinical symptoms and respiratory polygraphs, which can be used as an alternative to surgery.

Article Details

Author Biographies

Pham Duc Huy,

 

 

Dao Hoa Phuong,

 

 

Pham Dang Hoang Giang,

 

 

Pham Thi Thu Huyen,

 

 

Tran Minh Dien,

 

 

 

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