15. Clinical outcomes of modified natural cycle versus hormone replacement therapy for endometrial preparation for frozen embryo transfer

Pham Thi My, Ho Sy Hung, Le Thi Thu Hien, Nguyen Thi Huyen Trang, Pham Thi My Hanh

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Abstract

A single-center randomized clinical trial was conducted on 167 patients frozen embryo transfer in the period between August 2022 and March 2023 in the Andrology and Fertility Hospital of Hanoi. The results showed that the mean age in mNC and HRT groups was 31 ± 5 and 30 ± 5 years, respectively. The endometrial thickness on the day of Progesterone administration in the mNC group and the HRT group were 10.99 ± 1.46 and 10.70 ± 1.06mm, respectively. There was no significant difference between 2 groups regarding implantation rate, clinical pregnancy rate, and ongoing pregnancy rate. After adjusting for age, boday mass index, duration of infertility, type of infertility, history of miscarriage, number of failed embryo transfers, and endometrial thickness on the day of Progesterone administration, the number of good-quality embryos transferred showed that the clinical pregnancy rate in the HRT was trend higher than that mNC, but the relationship was not statistically significant with p > 0.05. The selection of a regimen to use for endometrial preparation for frozen embryo transfer depends on individualized patient treatment and each center.

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References

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