18. Characteristics of hypertension disorders in twin compared with singleton pregnancies

Nguyen Thi Huyen Anh, Nguyen Manh Thang, Truong Thanh Huong

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Abstract

The aim of this study was to determine the clinical characteristics and perinatal outcomes of hypertension disorders in twin pregnancy compared with singleton pregnancy. A cross-sectional study was conducted on 166 women with hypertension disorders in pregnancy (HDP) at the National Hospital of Obstetrics and Gynecology from March 2023 to June 2023. Of 166 women met the study criteria, 37 (23.3%) and 129 (77.7%) had twin and singleton pregnancies, respectively. Women with twin pregnancy were less likely to have a headache than women with singleton pregnancy (2.7% vs 17.8%; p = 0.021). There was no significant difference in the maternal adverse outcomes (eclampsia, abruptio placentae, and HELLP syndrome) between twins and singletons. Women with twin pregnancy had significantly higher rates of preterm delivery compared with singleton pregnancy (73.0% vs 54.3%; p = 0.042). However, the prevalence of fetal distress and intrauterine growth restriction in singleton pregnancies were higher than in twin pregnancies, with a statistically significant difference (13.2% vs 0%; p = 0.02 and 26.4% vs 10.8%; p = 0.047). The majority of birth weight in twin pregnancies was in the 1500 – 2499 gram range (59.5%), while the majority of birth weight in singleton pregnancies was more than 2500 gram (53.5%). Our study showed that women with hypertension disorders in singleton pregnancies have significantly higher prevalence of headache than in twin pregnancies. HDP have more severe fetal adverse outcomes (fetal distress and intrauterine growth restriction) in singleton than in twin pregnancies.

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References

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