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Published: 2023-09-20
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DOI: https://doi.org/10.52852/tcncyh.v169i8.1819
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Vol. 169 No. 8 (2023)
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Linh, N. T., Dũng, V. C., Thảo, B. P., & Hồng, N. T. T. (2023). 13. The concentration of serum 25-hydroxyvitamin d and glycemic control in children with diabetes mellitus type 1 at the national children’s hospital. Journal of Medical Research, 169(8), 106-113. https://doi.org/10.52852/tcncyh.v169i8.1819

13. The concentration of serum 25-hydroxyvitamin d and glycemic control in children with diabetes mellitus type 1 at the national children’s hospital

Nguyen Thi Linh, Vu Chi Dung, Bui Phuong Thao, Nguyen Thi Thuy Hong

Main Article Content

Abstract

Children with type 1 diabetes mellitus (T1DM) are at risk of vitamin D deficiency, which affects blood glucose control. A cross-sectional descriptive perspective recruited 66 T1DM children including 33 newly diagnosed T1DM patients and 33 established T1DM patients Objective to assess the concentration of serum 25(OH)D and glycemic status in T1DM children at the National Children’s Hospital. The concentration of 25(OH)D in T1DM children was 47 ± 16.8 nmol/L, the mean serum level in newly diagnosed T1DM children was 46.12 ± 17.14 nmol/L and in the established T1DM children was 48.2 ± 16.2 nmol/L however, the difference was not statistically significant (p > 0,05). 15.2% of T1DM chidren were 25(OH)D deficient, 39.4% were 25(OH)D insufficient and 45.5% were sufficient. The deficient and insufficient group was 55.5%. There was no association between the serum 25(OH)D concentration and HbA1c level in established T1DM children. Conclusion:Vitamin D deficiency is common in T1DM children.

Article Details

Keywords

25(OH)D concentration, diabetes mellitus type 1, glycemic control

References

1. Lưu Thị Mỹ Thục, Nguyễn Thái Hà, Bùi Thị Ngọc Ánh. Thiếu hụt vitamin D ở trẻ 6 - 11 tuổi tại Bệnh viện Nhi Trung ương và một số yếu tố liên quan. Tạp chí nhi khoa. 2019. 2019; 12: 58-64.
2. Chakhtoura M, Azar ST. The Role of Vitamin D Deficiency in the Incidence, Progression, and Complications of Type 1 Diabetes Mellitus. Int J Endocrinol. 2013; 2013: 148673. doi:10.1155/2013/148673.
3. Children and Adolescents: Standards of Medical Care in Diabetes-2022 | Diabetes Care | American Diabetes Association. https://diabetesjournals.org/care/article/45/Supplement_1/S208/138922/14-Children-and-Adolescents-Standards-of-Medical.
4. American Diabetes Association Professional Practice Committee. 2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2022. Diabetes Care. 2021; 45(Supplement_1): S17-S38. doi:10.2337/dc22-S002.
5. Consensus Statement: Global Consensus Recommendations on Prevention and Management of Nutritional Rickets - PMC. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4880117/.
6. Liu C, Wang J, Wan Y, et al. Serum vitamin D deficiency in children and adolescents is associated with type 1 diabetes mellitus. Endocr Connect. 2018; 7(12): 1275-1279. doi:10.1530/EC-18-0191.
7. Carakushansky M, Patel P, Ben Khallouq BA, et al. Prevalence of Vitamin D Deficiency in Children with Type 1 Diabetes Mellitus. Cureus. 12(4): e7836. doi:10.7759/cureus.7836.
8. Zabeen B, Nahar J, Ahmed B, et al. Vitamin D status in children and adolescents with type 1 diabetes in a specialized diabetes care centre in Bangladesh. Endocrinol Diabetes Metab. 2021; 5(1): e00312. doi:10.1002/edm2.312.
9. Abubaker S, Albasseet A, El-Abd KA, et al. Association Between Vitamin D Levels and Glycemic Control Among Adult Diabetic Patients in Riyadh, Saudi Arabia. Cureus. 2022; 14(6): e25919. doi:10.7759/cureus.25919.
10. Giri D, Pintus D, Burnside G, et al. Treating vitamin D deficiency in children with type I diabetes could improve their glycaemic control. BMC Res Notes. 2017; 10: 465. doi:10.1186/s13104-017-2794-3.