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Published: 2023-09-20
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DOI: https://doi.org/10.52852/tcncyh.v169i8.1820
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Vol. 169 No. 8 (2023)
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Hương, Đỗ T., Hùng, C. V., Thắng, L. N., Tuấn, Đặng A., & Hưng, M. V. (2023). 14. Epilepsy treatment outcome in pediatric patients with fo-cal cortical dysplasia at the National Children’s Hospital. Journal of Medical Research, 169(8), 114-122. https://doi.org/10.52852/tcncyh.v169i8.1820

14. Epilepsy treatment outcome in pediatric patients with fo-cal cortical dysplasia at the National Children’s Hospital

Do Thanh Huong, Cao Vu Hung, Le Nam Thang, Dang Anh Tuan, Mai Van Hung

Main Article Content

Abstract

The case series study consisting of 32 patients was performed to evaluate the outcome of epilepsy surgery from January 2016 to June 2023 in children with focal cortical dysplasia (FCD) at the National Children's Hospital. Most patients with FCD were treatment-resistant epilepsy, accounting for 93.8% and 50% of patients had the onset of seizures before 1 year of age. The rate of patients with postoperative seizure freedom was 62.5% (Engel class I and class Ia), 25% of patients had significant improved seizure outcome (Engle class II and class III), 20% of patients achieved complete cessation of antiepileptic drugs treatment, 37.5% of patients were able to switch from polytherapy to monotherapy. Complete resection of epileptic dysplasia lesions accounted for 46.9%. Incomplete resection of focal cortical dysplasia is the predictor of poor postsurgical outcome.

Article Details

Keywords

Focal cortical dysplasia, intractable epilepsy, children, epilepsy surgery

References

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