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Published: 2023-09-20
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DOI: https://doi.org/10.52852/tcncyh.v169i8.1829
Issue
Vol. 169 No. 8 (2023)
Section
Các bài báo
How to Cite
Trung, N. N., Thanh, V. T. N., Tùng, L. T., Chính, N. T. M., Sơn, N. T., Thuý, T. T. H., Hà, N. T. T., Anh, P. T. V., & Hằng, Đinh T. T. (2023). 32. A study on the hypoglycemic action of RA liquid extract in type 2 diabetic mice. Journal of Medical Research, 169(8), 271-278. https://doi.org/10.52852/tcncyh.v169i8.1829

32. A study on the hypoglycemic action of RA liquid extract in type 2 diabetic mice

Nguyen Ngoc Trung, Vu Thi Ngoc Thanh, Le Thanh Tung, Nguyen Thi Minh Chinh, Nguyen Truong Son, Tran Thi Hong Thuy, Nguyen Thi Thanh Ha, Pham Thi Van Anh, Dinh Thi Thu Hang

Main Article Content

Abstract

The purpose of this was to investigate the hypoglycemic action of RA liquid extract. Arachis hypoge linn extract is the main ingredient of RA, a product of the Military Institute of Traditional Medicine. This research included 2 stages: In the first stage, diabetes mellitus type 2 condition was induced in mice by a high fat diet and alloxan for 10 weeks; in the second stage, RA were administered orally to mice at 12 g/kg/day and 24 g/kg/day for 2 weeks. The results showed that both RA doses at 12 g/kg/day and 24 g/kg/day decreased the concentration of glucose, LDL-C, cholesterol and increased the HDL-C level in blood with improved micro-histological images on diabetes mellitus type 2 mice. These results accentuate that RA could be a potential agent for supporting the treatment of diabetes mellitus.

Article Details

Keywords

Arachis hypoge linn, diabetes mellitus, high fat diet, Swiss mice

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