20. Clinical and imaging features of ischemic stroke in children at the National Children's Hospital

Do Thuy Hang, Cao Vu Hung, Le Dinh Cong, Do Thanh Huong

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Abstract

The objective of the study was to describe the clinical features and craniocerebral imaging features of ischemic stroke in children. The study involved 123 children with ischemic stroke at the National Children's Hospital from January 2018 to May 2023. The data showed that the male/female ratio is 1.67/1. The most common age group for pediatric ischemic stroke was from 2months to 2-years old. The most common onset symptom was hemiparesis (59.3%). Seizures were more common in children under 2-years-old while headaches were more prevalent in the 6-to-11-years-old. Most patients had Glasgow scores above 13 points (80.5%). 64.2% of patients were diagnosed after 24 hours of onset. MRI is more effective than CT in the initial diagnosis of ischemic stroke. Diffusion weighted imaging on MRI had a sensitivity of 97.4% in the diagnosis of ischemic stroke. In summary, MRI should be considered as the initial imaging modality in suspected ischemic stroke to prevent delay in the diagnosis.

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References

1. Klučka J, Klabusayová E, Musilová T, et al. Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management. Children. 2021; 8(8): 649.
2. Wang JJ, Shi KL, Li JW, et al. Risk Factors for Arterial Ischemic and Hemorrhagic Stroke in Childhood. Pediatr Neurol. 2009; 40(4): 277-281.
3. Gerstl L, Weinberger R, von Kries R, et al. Risk factors in childhood arterial ischaemic stroke: Findings from a population-based study in Germany. Eur J Paediatr Neurol. 2018; 22(3): 380-386.
4. Mallick AA, Ganesan V, Kirkham FJ, et al. Diagnostic delays in paediatric stroke. J Neurol Neurosurg Psychiatry. 2015; 86(8): 917-921.
5. von Kummer R, Bourquain H, Bastianello S, et al. Early prediction of irreversible brain damage after ischemic stroke at CT. Radiology. 2001; 219(1): 95-100.
6. Mackay MT, Wiznitzer M, Benedict SL, et al. Arterial ischemic stroke risk factors: The international pediatric stroke study. Ann Neurol. 2011; 69(1): 130-140.
7. Tong E, Hou Q, Fiebach JB, Wintermark M. The role of imaging in acute ischemic stroke. Neurosurg Focus. 2014; 36(1): E3.
8. Mallick AA, Ganesan V, Kirkham FJ, et al. Childhood arterial ischaemic stroke incidence, presenting features, and risk factors: a prospective population-based study. Lancet Neurol. 2014; 13(1): 35-43.
9. Abend NS, Beslow LA, Smith SE, et al. Seizures as a Presenting Symptom of Acute Arterial Ischemic Stroke in Childhood. J Pediatr. 2011; 159(3): 479-483.
10. Simonsen CZ, Madsen MH, Schmitz ML, Mikkelsen IK, Fisher M, Andersen G. Sensitivity of diffusion- and perfusion-weighted imaging for diagnosing acute ischemic stroke is 97.5%. Stroke. 2015; 46(1): 98-101.
11. Sorensen AG, Buonanno FS, Gonzalez RG, et al. Hyperacute stroke: evaluation with combined multisection diffusion-weighted and hemodynamically weighted echo-planar MR imaging. Radiology. 1996; 199(2): 391-401.