21. Risk factors associated with surgical site infection in patients with hepato - pancreatico - biliary and gastrointestinal tract surgery: Review of 120 cases at Bach Mai Hospital

Tran Que Son, Nguyen The Hiep, Do Thi Bich Ngoc, Tran Hieu Hoc

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Abstract

Reducing the incidence of surgical site infection (SSI) is an important goal for surgical quality improvement. This study aimed to determine the incidence and factors associated with SSI in a group of patients undergoing surgery for pancreatico-hepato-biliary and gastrointestinal tract diseases. We conducted a prospective descriptive study at Bach Mai Hospital from January to June 2023. The demographic and perioperative characteristics were collected, and the main outcome was SSI within 30 days post-operation.In total, 120 patients were enrolled and SSI occurred in 9 patients (7.5%). The median age was 55.9 ± 18.0 years old (14 – 91). Univariate logistic regressions were conducted to predict risk factors of SSI after hepato-biliary and gastrointestinal diseases. There was a difference in SSI between factors ASA < III or ASA ≥ III (4.3% vs. 17.9%, p = 0.017); non-history or had a history of abdominal surgery (3.5% vs 10.5%, p = 0.01); laparoscopic or open surgery (0% vs 16.4%, p = 0.001). There was no difference in SSI rates between male or female factors (8.8% vs. 5.8%, p = 0.53); age < 60 or ≥ 60 (8.5% vs. 6.6%, p = 0.69); BMI (p = 0.196); comorbidity or non-comorbidity (8.6% vs. 6.5%, p = 0.65); duration of hospital stay ≤ 7 days or > 7 days (13% vs. 6.2%, p = 0.26); emergency or planned surgery (5.9% vs. 8.7%, p = 0.56) and surgical wound classification system (p = 0.06). Conclusion: This study provides the newest data on SSI after hepato-pancreatico-biliary and gastrointestinal tract surgery was 7.5%. Significant factors associated with SSI were ASA ≥ 3, history of abdominal surgery, and open surgery.

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Do Thi Bich Ngoc,

 

 

References

1. Kamboj M, Childers T, Sugalski J, et al. Risk of Surgical Site Infection (SSI) following Colorectal Resection Is Higher in Patients With Disseminated Cancer: An NCCN Member Cohort Study. Infect Control Hosp Epidemiol. 2018; 39(5): 555-562.
2. GlobalSurg C. Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study. Lancet Infect Dis. 2018; 18(5): 516-525.
3. Ouedraogo S, Kambire JL, Ouedraogo S, et al. Surgical Site Infection after Digestive Surgery: Diagnosis and Treatment in a Context of Limited Resources. Surg Infect (Larchmt). 2020;21(6):547-551.
4. Gantz O, Zagadailov P, Merchant AM. The Cost of Surgical Site Infections after Colorectal Surgery in the United States from 2001 to 2012: A Longitudinal Analysis. Am Surg. 2019; 85(2): 142-149.
5. Phạm Văn Tân. Nghiên cứu nhiễm khuẩn vết mổ các phẫu thuật tiêu hóa tại Bệnh Viện Bạch Mai. Luận án Tiến sĩ y học. Học viện Quân Y. 2016.
6. Nguyễn Thị Bích Ngọc, Nguyễn Hoàng, Trương Quang Trung. Đánh giá tình trạng nhiễm khuẩn vết mổ và một số yếu tố liên quan người bệnh phẫu thuật ống tiêu hóa tại Bệnh Viện Thanh Nhàn. Tạp chí Y học Việt Nam. 2021; 507(1): 161 - 165.
7. Phạm Minh Khuê, Vũ Thị Thanh Hương, Đoàn Văn Hiển. Thực trạng nhiễm khuẩn vết mổ tại Bệnh viện Hữu nghị Việt Tiệp, Hải Phòng năm 2021. Tạp chí y học dự phòng. 2022; 32(5): 140-147.
8. Phạm Thị Lan, Trịnh Thị Thoa, Nguyễn Vũ Hoàng Yến, và cộng sự. Nhiễm khuẩn vết mổ và các yếu tố liên quan tại Bệnh Viện Đại Học Y Dược TPHCM. Tạp chí Y học Việt Nam. 2023; 524(2): 349 - 354.
9. Sun C, Gao H, Zhang Y, Pei L, Huang Y. Risk Stratification for Organ/Space Surgical Site Infection in Advanced Digestive System Cancer. Front Oncol. 2021; 11:705335.
10. Vicentini C, Gianino MM, Corradi A, et al. Cost-Effectiveness Analysis of the Prophylactic Use of Ertapenem for the Prevention of Surgical Site Infections after Elective Colorectal Surgery. Antibiotics (Basel). 2021; 10(3).
11. Panos G, Mulita F, Akinosoglou K, et al. Risk of surgical site infections after colorectal surgery and the most frequent pathogens isolated: a prospective single-centre observational study. Med Glas (Zenica). 2021; 18(2): 438-443.
12. Watanabe M, Suzuki H, Nomura S, et al. Risk factors for surgical site infection in emergency colorectal surgery: a retrospective analysis. Surg Infect (Larchmt). 2014; 15(3): 256-261.
13. Hibbert D, Abduljabbar AS, Alhomoud SJ, Ashari LH, Alsanea N. Risk Factors for Abdominal Incision Infection after Colorectal Surgery in a Saudi Arabian Population: The Method of Surveillance Matters. Surg Infect (Larchmt). 2015; 16(3): 254-262.
14. Lawson EH, Hall BL, Ko CY. Risk factors for superficial vs deep/organ-space surgical site infections: implications for quality improvement initiatives. JAMA Surg. 2013; 148(9): 849-858.
15. Isik O, Kaya E, Sarkut P, Dundar HZ. Factors Affecting Surgical Site Infection Rates in Hepatobiliary Surgery. Surg Infect (Larchmt). 2015; 16(3): 281-286.
16. Kiran RP, El-Gazzaz GH, Vogel JD, Remzi FH. Laparoscopic approach significantly reduces surgical site infections after colorectal surgery: data from national surgical quality improvement program. J Am Coll Surg. 2010; 211(2): 232-238.
17. Aimaq R, Akopian G, Kaufman HS. Surgical site infection rates in laparoscopic versus open colorectal surgery. Am Surg. 2011; 77(10): 1290-1294.