7. Effectiveness of day 4 frozen embryo transfer
Main Article Content
Abstract
Currently, day 4 embryos are used for IVF transfer. However, it is not common and the effectiveness of the transfer is limited. This study aimed to initially evaluate the effectiveness of day 4 embryo transfer. This is a retrospective descriptive study of 149 cycles of day 4 frozen embryo transfer at the Center for IVF and Tissue Engineering, Hanoi Medical University Hospital from January 2022 to June 2023. The study evaluated the pregnancy outcome and affecting factors, including the quality of the transferred embryos, the number of transferred embryos, and the age of embryos at the freezing time. The mean age of patients was 30.21 ± 2.92 years old. The mean number of oocytes was 14.15 ± 7.04, mature oocytes mean was 10.88 ± 5.89. Fertilization rate was high at 85.43 ± 14.44 (%). Embryo quality was good, most were type 1 and type 2 embryos, accounting for over 90%. The results of our study showed that the pregnancy rate at day 4 embryo transfer was 57.7%. Transfer of at least 1 good embryo resulted in a statistically significant higher pregnancy rate compared to cycles without good embryos (63.4% and 16.67%, p < 0.0001). The number of transferred embryos and the age of embryos showed no statistically significant difference in pregnancy rate. However, further studies with larger sample sizes are needed to clarify the relationship between the number of embryos transferred and embryo age at freezing time with the outcome of day 4 embryo transfer. Our initial data suggested that day 4 embryo transfer could be applied widely for embryo transfer.
Article Details
Keywords
Frozen embryo transfer on day 4, IVF
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