33. Pregnancy results of frozen embryo transfer using natural and artificial cycles in uterine endometrial preparation protocols

Bach Thi Ha Thu, Tran Thi Thu Hang, Ho Nguyet Minh, Dang Thi Thu Thuy, Nguyen Thi Hai Van, Ho Sy Hung

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Abstract

Preparing the uterine endometrial for embryo transfer using artificial cycles and natural cycles are the two most popular protocols. This is a prospective study conducted on 85 patients undergoing frozen embryo transfer from September 2022 to August 2023 at the ART Central, National Hospital of Obstetrics and Gynecology to compare pregnancy rates between artificial and natural cycle protocols. The results showed there was no statistically significant difference in age, body mass index (BMI), cause of infertility, duration of infertility, type of infertility in the two groups. The uterine endometrial thickness on the day of progesterone in the artificial cycle group was statistically significantly thicker than inthe natural cycle (10.07 ± 2.53mm compared to 8.86 ± 2.31mm, p = 0.002). However, pregnancy rate (73.68% vs 63.33%, p = 0.71), clinical pregnancy (63.16% vs 56.67%, p = 0.84), biochemical pregnancy (10.53% vs. 6.67%, p = 0.69) was not statistically different between two groups. uterine endometrial preparation using natural cycle or artificial cycles for frozen embryo transfer gives equivalent pregnancy results. The cycle cancel rate in the natural cycles tends to be higher than the artificial cycle while the natural cycle requires less medication.

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References

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