Article Sidebar

PDF (Tiếng Việt)
Published: 2023-11-30
Abstract Views: 453
Views PDF (Tiếng Việt): 389
DOI: https://doi.org/10.52852/tcncyh.v172i11.2044
Issue
Vol. 172 No. 11 (2023)
Section
Các bài báo
How to Cite
Khải, T. Q., Thuý, N. T. D., Hùng, T. Đỗ, Phương, N. B. N., Nam, Đỗ H., Nghĩa, B. Q., Thơ, P. K. A., & Phương, N. M. (2023). 9. Severe respiratory syncytial virus-associated community-acquired pneumonia in children in Can Tho city. Journal of Medical Research, 172(11), 79-86. https://doi.org/10.52852/tcncyh.v172i11.2044

9. Severe respiratory syncytial virus-associated community-acquired pneumonia in children in Can Tho city

Tran Quang Khai, Nguyen Thi Dieu Thuy, Tran Do Hung, Nguyen Bich Nguyen Phuong, Do Hoang Nam, Bui Giang Nghĩa, Pham Kieu Anh Tho, Nguyen Minh Phuong

Main Article Content

Abstract

Respiratory syncytial virus (RSV) is one of the main causes of community-acquired pneumonia (CAP) in children. Microbiological co-infection in children with severe RSV-associated CAP is of significant research interest because of its association with antibiotic use. This analysis of 61 children with severe RSV-associated CAP showed that the disease usually occurs in children <2 years old (70.5%). Common clinical symptoms, such as fever, cough, rapid breathing, and crackles in the lungs, accounted for over 85% of the cases. Real-time PCR testing of nasopharyngeal fluid revealed that 93.4% of children had bacterial co-infection. The two most common bacteria in co-infection were Streptococus pneumoniae and Haemophilus influenzae. These results underscores that antibiotics remain an important treatment for children with severe RSV-associated CAP.

Article Details

Keywords

Respiratory syncytial virus, community-acquired pneumonia, children, Can Tho city

References

1. Chatterjee A, Mavunda K, Krilov LR. Current State of Respiratory Syncytial Virus Disease and Management. Infect Dis Ther. 2021; 10(Suppl 1):5-16.
2. Leung AKC, Wong AHC, Hon KL. Community-Acquired Pneumonia in Children. Recent Pat Inflamm Allergy Drug Discov. 2018; 12(2): 136-144.
3. Shi T, McAllister DA, O’Brien KL, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study. The Lancet. 2017; 390(10098): 946-958.
4. Zhou H, Thompson WW, Viboud CG, et al. Hospitalizations associated with influenza and respiratory syncytial virus in the United States, 1993-2008. Clin Infect Dis. 2012; 54(10): 1427-1436.
5. Li Y, Wang X, Blau DM, et al. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019: a systematic analysis. Lancet. 2022; 399(10340): 2047-2064.
6. WHO Guidelines Approved by the Guidelines Review Committee. In: Pocket Book of Hospital Care for Children: Guidelines for the Management of Common Childhood Illnesses. Geneva: World Health Organization Copyright © World Health Organization 2013.; 2013.
7. Michael H, Julia C, Nicky C, et al. British Thoracic Society guidelines for the management of community acquired pneumonia in children: update 2011. Thorax. 2011; 66(Suppl 2):ii1.
8. Lê Thị Hồng Hanh, Hoàng Thị Thu Hằng, Nguyễn Thị Lê, Hoàng Phương Thanh, Đặng Mai Liên. Đặc điểm dịch tễ học lâm sàng ở trẻ viêm phổi nặng có nhiễm RSV tại Trung tâm Hô hấp Bệnh viện Nhi Trung ương. Tạp chí nghiên cứu thực hành và Nhi khoa. 2020; 4(5): 1-9.
9. Hoàng Trung Thanh, Nguyễn Thị Yến, Phạm Thu Nga. Đặc điểm lâm sàng, cận lâm sàng viêm phế quản phổi nhiễm RSV (respiratory syncytial virus) ở trẻ em tại Bệnh viện Sản Nhi Vĩnh Phúc. Tạp chí Y học Việt Nam. 2021; 505(2).
10. Gea-Izquierdo E, Gil-Prieto R, Hernández-Barrera V, Gil-de-Miguel Á. Respiratory syncytial virus-associated hospitalization in children aged <2 years in Spain from 2018 to 2021. Hum Vaccin Immunother. 2023; 19(2): 2231818.
11. Nguyễn Ngọc Văn, Lê Thị Minh Hương. Đặc điểm lâm sàng viêm phổi do virus ở trẻ em dưới 5 tuổi tại Bệnh viện Nhi Trung Ương. Tạp chí Nhi khoa. 2023; 16(1).
12. Lin HC, Liu YC, Hsing TY, et al. RSV pneumonia with or without bacterial co-infection among healthy children. J Formos Med Assoc. 2022; 121(3): 687-693.
13. McCullers JA. Insights into the interaction between influenza virus and pneumococcus. Clin Microbiol Rev. 2006; 19(3): 571-582.
14. Galván JM, Rajas O, Aspa J. Review of Non-Bacterial Infections in Respiratory Medicine: Viral Pneumonia. Arch Bronconeumol. 2015; 51(11): 590-597.
15. Liu YN, Zhang YF, Xu Q, et al. Infection and co-infection patterns of community-acquired pneumonia in patients of different ages in China from 2009 to 2020: a national surveillance study. Lancet Microbe. 2023; 4(5): e330-e339.
16. Li Y, Pillai P, Miyake F, Nair H. The role of viral co-infections in the severity of acute respiratory infections among children infected with respiratory syncytial virus (RSV): A systematic review and meta-analysis. J Glob Health. 2020; 10(1): 010426.