12. Status of alcohol withdrawal and some related factors at Hanoi Mental Hospital

Pham The Van, Duong Minh Tam

Main Article Content

Abstract

This study aimed to describe the prevalence of alcohol withdrawal and analyze some factors related to the severity level of alcohol withdrawal among 103 inpatients at Hanoi Mental Hospital. Alcohol withdrawal was determined using the ICD-10 diagnostic criteria. At the time of admission, the prevalence of alcohol withdrawal was 20.4%, and within 24 hours, the prevalence increased to 97.1%. After 48 hours of treatment, only 1.9% of patients were in severe alcohol withdrawal. Severe alcohol withdrawal is significantly more likely in patients with increased mean red blood cell volume (OR = 3.2; p = 0.005) and thrombocytopenia (OR = 2.6; p = 0.024). This study demonstrated the dynamic changes of alcohol withdrawal in inpatient settings, highlighting key clinical factors influencing the severity of withdrawal.

Article Details

References

1. American Psychiatric Association. Substance-Related and Addictive Disorder. Diagnostic Anh Statistical Manual of Mental Disorders: DSM-5TM. Fifth Edition. American Psychiatric Publishing; 2013.
2. Rehm J, Shield K, Rehm M, Gmel G, Frick U. Alcohol Consumption, Alcohol Dependence and Attributable Burden of Disease in Europe: Potential Gains From Effective Interventions for Alcohol Dependence: (506502014-001). Published online 2012. doi:10.1037/e506502014-001.
3. Lê Anh Tuấn, Lý Trần Tình. Lạm Dụng Rượu, Nghiện Rượu ở Hà Nội. Nhà xuất bản Hà Nội; 2010.
4. Sullivan JT, Sykora K, Schneiderman J, Naranjo CA, Sellers EM. Assessment of Alcohol Withdrawal: the revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar). Addiction. 1989; 84(11): 1353-1357. doi:10.1111/j.1360-0443.1989.tb00737.x.
5. Nông Thế Đoàn. Đánh Giá Hiệu Quả Lâm Sàng Phác Đồ Điều Trị Phối Hợp Diazepam và Phenobarbital Trong Điều Trị Hội Chứng Cai Rượu. Luận văn Thạc sĩ Y học. Đại học Y Hà Nội; 2018.
6. Bùi Nguyễn Hồng Bảo Ngọc. Đặc Điểm Lâm Sàng và Yếu Tố Tiên Lượng Trạng Thái Cai Rượu ở Bệnh Nhân Điều Trị Nội Trú. Luận văn bác sỹ chuyên khoa cấp II. Đại học Y Hà Nội; 2021.
7. Monte R, Rabuñal R, Casariego E, Bal M, Pértega S. Risk factors for delirium tremens in patients with alcohol withdrawal syndrome in a hospital setting. European Journal of Internal Medicine. 2009; 20(7): 690-694. doi:10.1016/j.ejim.2009.07.008.
8. Phạm Thế Văn. Đặc Điểm Lâm Sàng và Tiến Triển Của Hội Chứng Cai Rượu ở Bệnh Nhân Điều Trị Nội Trú Tại Viện Sức Khỏe Tâm Thần. Luận văn Thạc sĩ Y học. Đại học Y Hà Nội; 2019.
9. Pribék IK, Kádár BK, Péter L, et al. Seasonality and Delirium Tremens in Hospitalized Patients with Alcohol Dependence Syndrome. Eur Addict Res. 2023; 29(2): 83-91. doi:10.1159/000527973.
10. Bakhla AK, Khess CRJ, Verma V, Hembram M, Praharaj SK, Soren S. Factor Structure of CIWA-Ar in Alcohol Withdrawal. Journal of Addiction. 2014; 2014: 1-7. doi:10.1155/2014/745839.
11. Eyer F, Schuster T, Felgenhauer N, et al. Risk Assessment of Moderate to Severe Alcohol Withdrawal--Predictors for Seizures and Delirium Tremens in the Course of Withdrawal. Alcohol and Alcoholism. 2011; 46(4): 427-433. doi:10.1093/alcalc/agr053.
12. Kim DW, Kim HK, Bae EK, Park SH, Kim KK. Clinical predictors for delirium tremens in patients with alcohol withdrawal seizures. The American Journal of Emergency Medicine. 2015; 33(5): 701-704. doi:10.1016/j.ajem.2015.02.030.
13. Berggren U, Fahlke C, Berglund KJ, Blennow K, Zetterberg H, Balldin J. Thrombocytopenia in Early Alcohol Withdrawal is Associated with Development of Delirium Tremens or Seizures. Alcohol and Alcoholism. 2009; 44(4): 382-386. doi:10.1093/alcalc/agp012.
14. Findley JK, Park LT, Siefert CJ, et al. Two Routine Blood Tests-Mean Corpuscular Volume and Aspartate Aminotransferase-as Predictors of Delirium Tremens in Trauma Patients. Journal of Trauma: Injury, Infection & Critical Care. 2010; 69(1): 199-201. doi:10.1097/TA.0b013e3181bee583.