14. Clinical characteristics and risk factors of paradoxical hypertension after repair of coarctation of the aorta at National Children’s Hospital

Tran Ngoc Hieu, Le Hong Quang, Le Trong Phu, Dang Thi Hai Van

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Abstract

Paradoxical hypertension after repair of coarctation of the aorta is a well-recognized phenomenon, typically occuring within 1 week after surgery. This is a retrospective descriptive study of 115 patients who were diagnosed with coarctation of the aorta and had surgery to repair coarctation of the aorta at Vietnam National Children's Hospital from June 2018 to June 2023. Among the 115 patients, the proportion of paradoxical hypertension is 77%. The onset of hypertension usually occurred in the first 6 hours after surgery. Systolic hypertension peaked in about 6 to 12 hours after surgery and diastolic hypertension peaked in about 72 to 96 hours after surgery. Stage 2 hypertension accounted for 79.8% of cases, mainly occurring within 24 hours after surgery. All patients had systolic hypertension, 6% patients had isolated systolic hypertension, and 92.1% had both systolic and diastolic hypertension. Multivariate regression analysis showed that age at surgery > 1-month, preoperative hypertension and requiring postoperative vasopressors and inotropes were independent risk factors for paradoxical hypertension.

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References

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