31. Health-related quality of life and related factors in multidrug-resistant tuberculosis patients undergoing treatment in Vietnam
Main Article Content
Abstract
Patients with multidrug-resistant tuberculosis may experience problems affecting their quality of life both physically and mentally. This study aimed to assess the health-related quality of life and associated factors in multidrug-resistant tuberculosis patients treated in the Programmatic Management of Drug-Resistant Tuberculosis Program in Vietnam. The health-related quality of life of patients was assessed through the SF-36v2 questionnaire. The mean health-related quality of life score after 6 months of treatment in the physical component was 44.2 ± 10.5, lower than the general population. The mental component summary was 49.8 ± 11.4, equivalent to the general population. In multivariate analysis, younger patients, males, those with middle school education, and high school education had higher mean physical component scores than their counterparts. Patients living with others had higher mean mental component scores than those living alone. These findings underscore the importance of not solely focusing on disease managment but also on monitoring adverse drug reactions, combining physiotherapy and functional rehabilitation approaches to enhance patients' physical health.
Article Details
Keywords
Health-related quality of life, multidrug-resistant tuberculosis patient, SF-36v2
References
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11. Watkins RE, Plant AJ, Sang D, O’Rourke T, Gushulak B. Development of a Vietnamese version of the Short form-36 Health Survey. Asia-Pacific journal of public health. 2000; 12(2): 118-23. doi:10.1177/101053950001200211.
12. Chamla D. The assessment of patients’ health-related quality of life during tuberculosis treatment in Wuhan, China. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. Sep 2004; 8(9): 1100-6.
13. Maruish M.E. User’s manual for the SF-36v2 Health Survey (3rd ed). RI: QualityMetric Incorporated.
14. Wu S, Zhang Y, Sun F, et al. Adverse Events Associated With the Treatment of Multidrug-Resistant Tuberculosis: A Systematic Review and Meta-analysis. American journal of therapeutics. Mar-Apr 2016; 23(2): e521-30. doi:10.1097/01.mjt.0000433951.09030.5a.
15. Singla N, Singla R, Fernandes S, Behera D. Post treatment sequelae of multi-drug resistant tuberculosis patients. The Indian journal of tuberculosis. Oct 2009; 56(4): 206-12.
16. Jaber AAS, Ibrahim B. Health-related quality of life of patients with multidrug-resistant tuberculosis in Yemen: prospective study. Health and quality of life outcomes. Aug 16 2019; 17(1): 142. doi:10.1186/s12955-019-1211-0.
17. Nguyễn Thị Thanh Vân. Chất lượng cuộc sống của bệnh nhân điều trị lao đa kháng thuốc tại Thành phố Hồ Chí Minh. Trường Đại học kinh tế Thành phố Hồ Chí minh; 2020.
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22. Rafiq M, Saqib SE, Atiq M. Health-Related Quality of Life of Tuberculosis Patients and the Role of Socioeconomic Factors: A Mixed-Method Study. The American journal of tropical medicine and hygiene. Oct 4 2021; 106(1): 80-87. doi:10.4269/ajtmh.21-0494.
23. Hassan WA, Darwish AM. Impact of pulmonary tuberculosis on menstrual pattern and fertility. Clin Respir J. Jul 2010; 4(3): 157-61. doi:10.1111/j.1752-699X.2009.00166.x.
24. Võ Đình Thục Nhân. Chất lượng cuộc sống và một số yếu tố liên quan ở bệnh nhân lao phổi đang điều trị ngoại trú tại Trung tâm Y tế quận Gò Vấp Thành Phố Hồ Chí Minh năm 2022. Luận văn Thạc sĩ Y tế công cộng. Trường Đại học Y tế Công cộng; 2022.
25. Darvishpoor Kakhki A, Masjedi MR. Factors Associated with Health-Related Quality of Life in Tuberculosis Patients Referred to the National Research Institute of Tuberculosis and Lung Disease in Tehran. Tuberc Respir Dis (Seoul). Oct 2015; 78(4): 309-14. doi:10.4046/trd.2015.78.4.309.
26. Howley MM, Rouse CD, Katz DJ, Colson PW, Hirsch-Moverman Y, Royce RA. Knowledge and Attitudes About Tuberculosis Among U.S.-Born Blacks and Whites with Tuberculosis. J Immigr Minor Health. Oct 2015; 17(5): 1487-95. doi:10.1007/s10903-014-0105-9.
27. Adeyeye OO, Ogunleye OO, Coker A, et al. Factors Influencing Quality of Life and Predictors of Low Quality of Life Scores in Patients on Treatment for Pulmonary Tuberculosis: A Cross Sectional Study. J Public Health Afr. Jun 29 2014; 5(2): 366. doi:10.4081/jphia.2014.366.
28. Numpong S, Kengganpanich M, Kaewkungwal J, et al. Confronting and Coping with Multidrug-Resistant Tuberculosis: Life Experiences in Thailand. Qual Health Res. Jan 2022; 32(1): 159-167. doi:10.1177/10497323211049777.
2. World Health Organization. Global tuberculosis report 2020. 2020
3. Chương trình chống lao quốc gia. Báo cáo tổng kết chương trình chống lao quốc gia 2021. 2021;
4. World Health Organization. Global tuberculosis report 2021. 2021;
5. Isaakidis P, Rangan S, Pradhan A, Ladomirska J, Reid T, Kielmann K. ‘I cry every day’: experiences of patients co-infected with HIV and multidrug-resistant tuberculosis. Tropical medicine & international health : TM & IH. Sep 2013; 18(9): 1128-1133. doi:10.1111/tmi.12146.
6. Jaber AA, Khan AH, Syed Sulaiman SA, Ahmad N, Anaam MS. Evaluation of Health-Related Quality of Life among Tuberculosis Patients in Two Cities in Yemen. PLoS One. 2016; 11(6): e0156258. doi:10.1371/journal.pone.0156258.
7. Bauer M, Leavens A, Schwartzman K. A systematic review and meta-analysis of the impact of tuberculosis on health-related quality of life. Qual Life Res. Oct 2013; 22(8): pp. 2213-35. doi:10.1007/s11136-012-0329-x.
8. Alene KA, Clements ACA, McBryde ES, et al. Mental health disorders, social stressors, and health-related quality of life in patients with multidrug-resistant tuberculosis: A systematic review and meta-analysis. The Journal of infection. Nov 2018; 77(5): 357-367. doi:10.1016/j.jinf.2018.07.007.
9. Velen K, Viet Nhung N, Dang T, et al. Harnessing new mHealth technologies to Strengthen the Management of Multidrug-Resistant Tuberculosis in Vietnam (V-SMART trial): a protocol for a randomised controlled trial. BMJ Open. 06/22 2022; 12doi:10.1136/bmjopen-2021-052633.
10. Ahmad N, Javaid A, Syed Sulaiman SA, et al. Effects of Multidrug Resistant Tuberculosis Treatment on Patients’ Health Related Quality of Life: Results from a Follow Up Study. PLOS ONE. 2016; 11(7): e0159560. doi:10.1371/journal.pone.0159560.
11. Watkins RE, Plant AJ, Sang D, O’Rourke T, Gushulak B. Development of a Vietnamese version of the Short form-36 Health Survey. Asia-Pacific journal of public health. 2000; 12(2): 118-23. doi:10.1177/101053950001200211.
12. Chamla D. The assessment of patients’ health-related quality of life during tuberculosis treatment in Wuhan, China. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease. Sep 2004; 8(9): 1100-6.
13. Maruish M.E. User’s manual for the SF-36v2 Health Survey (3rd ed). RI: QualityMetric Incorporated.
14. Wu S, Zhang Y, Sun F, et al. Adverse Events Associated With the Treatment of Multidrug-Resistant Tuberculosis: A Systematic Review and Meta-analysis. American journal of therapeutics. Mar-Apr 2016; 23(2): e521-30. doi:10.1097/01.mjt.0000433951.09030.5a.
15. Singla N, Singla R, Fernandes S, Behera D. Post treatment sequelae of multi-drug resistant tuberculosis patients. The Indian journal of tuberculosis. Oct 2009; 56(4): 206-12.
16. Jaber AAS, Ibrahim B. Health-related quality of life of patients with multidrug-resistant tuberculosis in Yemen: prospective study. Health and quality of life outcomes. Aug 16 2019; 17(1): 142. doi:10.1186/s12955-019-1211-0.
17. Nguyễn Thị Thanh Vân. Chất lượng cuộc sống của bệnh nhân điều trị lao đa kháng thuốc tại Thành phố Hồ Chí Minh. Trường Đại học kinh tế Thành phố Hồ Chí minh; 2020.
18. Thiruvalluvan E, Thomas B, Suresh C, Sellappan S, Muniyandi M, Watson B. The psychosocial challenges facing multi drug resistance tuberculosis patients: A qualitative study. SAARC Journal of Tuberculosis, Lung Diseases and HIV/AIDS. 07/12 2017; 14:14. doi:10.3126/saarctb.v14i1.17724.
19. Vũ Thị Lý. Chất lượng cuộc sống của bệnh nhân lao đa kháng thuốc tại Hà Nội năm 2021. Luận văn Thạc sĩ Y tế công cộng. Trường Đại học Y Hà Nội; 2022.
20. Guo N, Marra F, Marra CA. Measuring health-related quality of life in tuberculosis: a systematic review. Health and quality of life outcomes. Feb 18 2009; 7:14. doi:10.1186/1477-7525-7-14.
21. Malik M, Nasir R, Hussain A. Health Related Quality of Life among TB Patients: Question Mark on Performance of TB DOTS in Pakistan. J Trop Med. 2018; 2018: 2538532. doi:10.1155/2018/2538532.
22. Rafiq M, Saqib SE, Atiq M. Health-Related Quality of Life of Tuberculosis Patients and the Role of Socioeconomic Factors: A Mixed-Method Study. The American journal of tropical medicine and hygiene. Oct 4 2021; 106(1): 80-87. doi:10.4269/ajtmh.21-0494.
23. Hassan WA, Darwish AM. Impact of pulmonary tuberculosis on menstrual pattern and fertility. Clin Respir J. Jul 2010; 4(3): 157-61. doi:10.1111/j.1752-699X.2009.00166.x.
24. Võ Đình Thục Nhân. Chất lượng cuộc sống và một số yếu tố liên quan ở bệnh nhân lao phổi đang điều trị ngoại trú tại Trung tâm Y tế quận Gò Vấp Thành Phố Hồ Chí Minh năm 2022. Luận văn Thạc sĩ Y tế công cộng. Trường Đại học Y tế Công cộng; 2022.
25. Darvishpoor Kakhki A, Masjedi MR. Factors Associated with Health-Related Quality of Life in Tuberculosis Patients Referred to the National Research Institute of Tuberculosis and Lung Disease in Tehran. Tuberc Respir Dis (Seoul). Oct 2015; 78(4): 309-14. doi:10.4046/trd.2015.78.4.309.
26. Howley MM, Rouse CD, Katz DJ, Colson PW, Hirsch-Moverman Y, Royce RA. Knowledge and Attitudes About Tuberculosis Among U.S.-Born Blacks and Whites with Tuberculosis. J Immigr Minor Health. Oct 2015; 17(5): 1487-95. doi:10.1007/s10903-014-0105-9.
27. Adeyeye OO, Ogunleye OO, Coker A, et al. Factors Influencing Quality of Life and Predictors of Low Quality of Life Scores in Patients on Treatment for Pulmonary Tuberculosis: A Cross Sectional Study. J Public Health Afr. Jun 29 2014; 5(2): 366. doi:10.4081/jphia.2014.366.
28. Numpong S, Kengganpanich M, Kaewkungwal J, et al. Confronting and Coping with Multidrug-Resistant Tuberculosis: Life Experiences in Thailand. Qual Health Res. Jan 2022; 32(1): 159-167. doi:10.1177/10497323211049777.