20. Một số yếu tố liên quan đến kết quả điều trị trẻ mắc viêm não Nhật Bản tại Bệnh viện Nhi Trung ương

Abstract

The objective of the study is to describe the treatment outcomes of Japanese encephalitis and identify factors influencing these outcomes in children at the National Children's Hospital. This cross-sectional descriptive study involved 71 Japanese encephalitis patients under 16 years old, receiving treatment at the Center for Tropical Diseases - National Children's Hospital from June 2022 to August 2023. The results showed no fatalities among the patients, 45% recovered completely, and 55% presented with sequelae upon discharged from the hospital. Treatment interventions included mechanical ventilation for 43.7% of patients and tracheostomy for 15.5%. Factors associated with having sequelae of Japanese encephalitis were respiratory failure on admission (OR = 5, 95%CI: 1.4 - 21); limb paralysis (OR = 5.2, 95%CI: 1.04 - 26); Glasgow score < 11 (OR = 6.7, 95%CI: 2 - 22.6); fever duration > 7 days (OR = 6.7, 95%CI: 1.97 - 22.6); treatment for increased intracranial pressure lasting ≥ 3 days (OR = 11.6, 95%CI: 3.8 - 35). In conclusion, Glasgow score at admission < 11 points and treatment duration for increased intracranial pressure ≥ 3 days were significant factors associated with sequelae of Japanese encephalitis patients.