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Published: 2024-02-27
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DOI: https://doi.org/10.52852/tcncyh.v174i1.2204
Issue
Vol. 174 No. 1 (2024)
Section
Các bài báo
How to Cite
Ngọc, N. D. ., Khánh, T. V. ., Thúy, N. T. ., Phương, L. T. ., Thịnh, T. H. ., Thái, P. V. ., Tâm, L. Đức ., & Hùng, K. Đình . (2024). 4. Studying miRNA-29b expression level in glioma patients. Journal of Medical Research, 174(1), 27-33. https://doi.org/10.52852/tcncyh.v174i1.2204

4. Studying miRNA-29b expression level in glioma patients

Nguyen Duy Ngoc, Tran Van Khanh, Nguyen Thu Thuy, Le Thi Phuong, Tran Huy Thinh, Pham Van Thai, Le Duc Tam, Kieu Dinh Hung

Main Article Content

Abstract

Gliomas develop from undifferentiated or poorly differentiated glial cells in the brain. Many studies have shown that the pathogenesis of glioma relates to the variable expression levels of miRNAs. miRNA-29b promotes apoptosis and inhibits proliferation in glioma cells. This study aimed to determine miRNA-29b expression level in peripheral blood of glioma patients. The expression of miRNA-29b was detected in plasma from 62 post-operative gliomas and 62 healthy controls using realtime-PCR technique. The results showed that the expression level of miRNA-29b was not different between gliomas and controls. We found no corelation between miRNA-29b and characteristics of glioma group.

Article Details

Keywords

Gliomas, miRNA-29b, realtime-PCR

References

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