9. Nutritional status in older patients with parkinson’s disease and associated factors
Main Article Content
Abstract
This study was conducted to assess factors related to the nutrition status among older patients with Parkinson’s disease (PD) in 2023. A cross-sectional study was conducted on participants aged over 60 years old having PD at the National Geriatric Hospital from February 2023 to October 2023. The nutritional status was assessed using Mini Nutritional Assessment Short Form (MNA – SF) questionnaires. A total of 200 study participants diagnosed for PD with the mean age of 68.7 ± 5.2 years old and the female/male ratio was approximately 1.5. The prevalence of malnourished and at risk of malnutrition were 7.5%, 41.5%, respectively. Multiple logistic regression analysis showed that female (OR = 2.34, 95% CI 1.18 – 4.63, p = 0.014), dopamine agonist (OR = 0.36, 95% CI 0.16 – 0.82, p = 0.009) and depressive symptom (OR = 2.11, 95% CI 1.02 - 4.40, p = 0.044) were risk factors for malnutrition in older patients with PD. Screening for malnutrition is necessary among older patients with PD, especially in female, using dopamine agonist, and having depressive symptoms.
Article Details
Keywords
MNA-SF, Parkinson disease, nutritional status
References
2. Floriano EN, Alves JF, Almeida IAD, Souza RBD, Christofoletti G, Santos SMS. Dual task performance: a comparison between healthy elderly individuals and those with Parkinson’s disease. Fisioter Em Mov. 2015; 28(2): 251-258. doi:10.1590/0103-5150.028.002.AO05.
3. Akbar U, He Y, Dai Y, et al. Weight Loss and Impact on Quality of Life in Parkinson’s Disease. PLoS ONE. 2015; 10(5): e0124541. doi:10.1371/journal.pone.0124541.
4. Beyer PL, Palarino MY, Michalek D, Busenbark K, Koller WC. Weight change and body composition in patients with Parkinson’s disease. J Am Diet Assoc. 1995; 95(9): 979-983. doi:10.1016/S0002-8223(95)00269-3.
5. De Rui M, Inelmen EM, Trevisan C, Pigozzo S, Manzato E, Sergi G. Parkinson’s disease and the non-motor symptoms: hyposmia, weight loss, osteosarcopenia. Aging Clin Exp Res. 2020; 32(7): 1211-1218. doi:10.1007/s40520-020-01470-x.
6. Barichella M, Cereda E, Madio C, et al. Nutritional risk and gastrointestinal dysautonomia symptoms in Parkinson’s disease outpatients hospitalised on a scheduled basis. Br J Nutr. 2013; 110(2): 347-353. doi:10.1017/S0007114512004941.
7. Capecci M, Petrelli M, Emanuelli B, et al. Rest energy expenditure in Parkinson’s disease: role of disease progression and dopaminergic therapy. Parkinsonism Relat Disord. 2013; 19(2): 238-241. doi:10.1016/j.parkreldis.2012.10.016.
8. Phillips MB, Foley AL, Barnard R, Isenring EA, Miller MD. Nutritional screening in community-dwelling older adults: a systematic literature review. Asia Pac J Clin Nutr. 2010; 19(3): 440-449.
9. Cereda E. Mini nutritional assessment. Curr Opin Clin Nutr Metab Care. 2012; 15(1): 29-41. doi:10.1097/MCO.0b013e32834d7647.
10. Ongun N. Does nutritional status affect Parkinson’s Disease features and quality of life? PloS One. 2018; 13(10): e0205100. doi:10.1371/journal.pone.0205100.
11. Van Steijn J, Van Harten B, Flapper E, et al. The nutritional status of Dutch elderly patients with Parkinson’s disease. J Nutr Health Aging. 2014; 18(6): 601-607. doi:10.1007/s12603-014-0444-1.
12. Yang T, Zhan Z, Zhang L, et al. Prevalence and Risk Factors for Malnutrition in Patients With Parkinson’s Disease. Front Neurol. 2020; 11. doi:10.3389/fneur.2020.533731.
13. Fu J, Li Z, Wang F, Yu K. Prevalence of malnutrition/malnutrition risk and nutrition-related risk factors among patients with Parkinson’s disease: systematic review and meta-analysis. Nutr Neurosci. 2022; 25(10): 2228-2238. doi:10.1080/1028415X.2021.1948655.
14. Artaud F, Lee PC, Mangone G, Vidailhet M, Corvol JC, Elbaz A. Longitudinal association between dopamine agonists and weight in Parkinson’s disease. Parkinsonism Relat Disord. 2020; 80: 158-164. doi:10.1016/j.parkreldis.2020.09.037.
15. Panarese A, Pesce F, Porcelli P, et al. Chronic functional constipation is strongly linked to vitamin D deficiency. World J Gastroenterol. 2019; 25(14): 1729-1740. doi:10.3748/wjg.v25.i14.1729.