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Published: 2024-07-31
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DOI: https://doi.org/10.52852/tcncyh.v179i6.2478
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Vol. 179 No. 6 (2024)
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Toàn, T. T., Thỉnh, N. V., Ánh, D. T. N., & Tờ, T. V. (2024). 10. Tumor infiltrating Lymphocytes and relationship with histological characteristics in triple-negative breast carcinoma. Journal of Medical Research, 179(6), 90-98. https://doi.org/10.52852/tcncyh.v179i6.2478

10. Tumor infiltrating Lymphocytes and relationship with histological characteristics in triple-negative breast carcinoma

Tran Trung Toan, Nguyen Van Thinh, Duong Thi Ngoc Anh, Ta Van To

Main Article Content

Abstract

This study aims to determine the rate of tumor infiltrating lymphocytes (TILs) and compare it with histopathological features of triple-negative breast cancer (TNBC). We conducted a study on 214 TNBC patients diagnosed and treated at K hospital from October 2021 to December 2023. All patients were female, average age 53.6 ± 13.1 years (range 28-90 years). The average rate of TILs is 20.0 ± 25.7%, the TILs 10% has the highest rate with 37 cases (accounting for 17.3%). The intermediate TILs group (10 - 40%, group B) accounts for the highest proportion (49.1%). With a dividing threshold of 50%, patients with non-predominant TILs (< 50%) accounted for the majority in the study (76.2%), compared with the characteristics of histopathological type and histological grade, the difference statistically significant difference p < 0.05. Consequently, we suggest that it is necessary to routinely evaluate TILs in the practice of pathological diagnosis for TNBC.

Article Details

Keywords

Tumor infiltrating lymphocytes, Breast cancer, Triple-negative breast carcinoma

References

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