20. Midterm outcomes after the arterial switch operation at Vietnam National Children’s Hospital in the period 2010-2020

Nguyen Tuan Mai, Nguyen Huu Uoc, Nguyen Huu Nhat, Nguyen Quy Khuong, Doan Vuong Anh, Nguyen Ly Thinh Truong

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Abstract

The purpose of the study was to evaluate the midterm outcomes and risk factors for early mortality and reoperation in patients undergoing an arterial switch operation at Vietnam National Children’s Hospital from 2010 to 2020. 558 patients with the median age at +27 (36) days, 73.5% of patients were male, median aortic cross-clamp time was 108 (53.8) minutes. Overall early mortality was 5.9%, and late mortality was 1.1%. Multivariate Cox regression showed: prolonged aortic cross-clamp time (HR = 1.01, 95% CI: 1.01-1.02, p < 0.01), weight less than 3kg at the time of ASO (HR = 3.56, 95% CI: 1.8 - 7.1, p < 0.01), and need for secondary aortic cross-clamp (HR = 5.2, 95% CI: 1.5 - 19.8, p < 0.01) as risk factors for overall early mortality. The rate of reoperation was 3.8%, patients who were diagnosed with DORV-TGA were at risk for reoperation (HR = 10.1; 95% CI: 2.7 - 38, p < 0.01).

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References

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