23. Characteristics of autoimmune bullous diseases in children
Main Article Content
Abstract
This retrospective, cross-sectional study aims to describe the clinical and paraclinical characteristics of certain autoimmune bullous diseases in children at the National Hospital of Dermatology and Venereology over 5 years, from January 2019 to December 2023. The results indicated that 26 patients with autoimmune bullous diseases were treated as inpatients. Linear IgA bullous dermatosis was the most common, with 16 cases reported. Additionally, there were 5 cases of bullous pemphigoid, 2 cases of pemphigus vulgaris, 2 cases of epidermolysis bullosa acquisita, and 1 case of IgA pemphigus. The mean age was 5.62 years, ranging from 1 to 14 years, with a male-to-female ratio of 15:11. The positive rate for direct immunofluorescence was 84.6%, while indirect immunofluorescence was positive in 69.3% of cases. Among those with linear IgA bullous dermatosis, the average age of onset was 4.4 years, with males more affected than females (11:5). The positive detection rate of linear IgA on direct immunofluorescence was 81.3%, and the circulating IgA detection rate in blood was 62.5%.
Article Details
Keywords
Autoimmune bullous diseases, bullous pemphigoid, IgA pemphigus, linear IgA bullous dermatosis, pemphigus vulgaris
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