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Published: 2024-09-11
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DOI: https://doi.org/10.52852/tcncyh.v180i7.2553
Issue
Vol. 180 No. 7 (2024)
Section
Các bài báo
How to Cite
Linh, Đỗ Đức, Giang, Đoàn T., Thành, Đinh T., & Đức, P. H. . (2024). 24. Correlation between pancreatic fat deposition by computed tomography with BMI and type 2 diabetes mellitus. Journal of Medical Research, 180(7), 213-222. https://doi.org/10.52852/tcncyh.v180i7.2553

24. Correlation between pancreatic fat deposition by computed tomography with BMI and type 2 diabetes mellitus

Do Duc Linh, Doan Thi Giang, Dinh Trung Thanh, Pham Hong Duc

Main Article Content

Abstract

The study aimed to determine the grade of intra-pancreatic fat deposition (IPFD) on computed tomography (CT) in normal people and evaluate the correlation with body mass index (BMI) and type 2 diabetes mellitus (T2DM). These indicators are intended to determine the grade of pancreatic fat deposition through observation (divided into 4 grade 0, 1, 2 and 3) and measuring HU determined on CT. A total of 208 people aged 47.6 ± 14.8 years old had abdominal CT scans and were determined not to be related to pancreatic inflammation or tumor. The results showed that grade 0,1 and 2 of the pancreatic head and tail accounted for 86.5%, 12% and 1.4% respectively; and 86.1%, 13%, and 1.0% respectively. There were no cases of grade 3 fat deposition. Age in people with grade 1 fat deposition was higher than that of grade 0 (p < 0.05). The average value of BMI gradually increases with the grade of IPFD from grade 0 to grade 2 (p < 0.05); Pancreatic density in underweight and obese people is lower than normal BMI (p < 0.05). There is agreement between the pancreatic grades in terms of observation and measurement of pancreatic density. Patients with T2DM had lower mean pancreatic density and higher grade of IPFD than those without this disease, 47.8 ± 4.7HU and 44.9 ± 7.6HU, respectively (p < 0.003).

Article Details

Keywords

Intra-pancreatic fat deposition, non-alcoholic fatty pancreas disease, fatty pancreas, MSCT

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