4. Morphological characteristics of the esophagogastric junction on high-resolution manometry in patients with reflux symptoms
Main Article Content
Abstract
Abnormalities in morphology and function of the esophagogastric junction (EGJ) play an important role in the pathogenesis of gastroesophageal reflux disease (GERD), but data in Vietnam is limited. A cross-sectional retrospective study was performed and data were collected from 856 patients with GerdQ score ≥ 8 from September 2020 to March 2023 to describe the EGJ morphology on high-resolution manometry (HRM) and its relationship with clinical symptoms and endoscopic characteristics. Mean age was 48.3 ± 13.8 years and 35.8% were male. The most common symptoms were regurgitation (81.9%), belching (70.1%) and heartburn (50.1%). On endoscopy, hiatal hernia accounted for only 4.3%. On HRM, 86 .4% of patients had EGJ type I (n = 740). The percentage of hiatal hernia (EGJ type III) was low, only 2.7%. Patients with hiatal hernia on HRM group had significantly higher average age and lower proportion of males. Median lower esophageal sphincter (LES) resting pressure, integrated relaxation pressure in 4 seconds (IRP4s) and esophagogastric junction contractile integral (EGJ-CI) in the EGJ type III group were lower compared to the other two group, but these data were not statistically significant.
Article Details
Keywords
Esophagogastric junction (EGJ), hiatal hernia, high-resolution manometry (HRM)
References
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