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Published: 2024-09-27
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DOI: https://doi.org/10.52852/tcncyh.v181i8.2631
Issue
Vol. 181 No. 8 (2024)
Section
Các bài báo
How to Cite
Thịnh, L. H., Dự, N. H., Thái, N. H., Mỹ, N. X., & Sơn, V. T. (2024). 16. Role of ultrasound markers for detection of fetal Trisomy 21. Journal of Medical Research, 181(8), 149-156. https://doi.org/10.52852/tcncyh.v181i8.2631

16. Role of ultrasound markers for detection of fetal Trisomy 21

Le Hong Thinh, Nguyen Huu Du, Nguyen Hoang Thai, Nguyen Xuan My, Vo Ta Son

Main Article Content

Abstract

The purpose of this research was to investigate the role of various ultrasound markers in fetal morphology ultrasound in prenatal screening for Down syndrome (trisomy 21). The study subjects included two groups: the first group consisted of 118 pregnant women who underwent prenatal diagnostic testing using QF-PCR technique with results indicating trisomy 21, and the second group consisted of 2329 pregnant women who underwent prenatal testing with normal fetal results. The results are as follow Trisomy 21 Group (Ultrasound Findings): Absent nasal bone:16.1%, increased nuchal translucency: 11.9%, ventriculomegaly: 9.3%, echogenic bowel: 3.4%, duodenal atresia: 1.7% and cystic hygroma: 2.5%. Ultrasound markers with a high positive predictive value in screening for trisomy 21 fetuses were duodenal atresia (40.0%), echogenic bowel (33.3%), nasal bone aplasia (30.6%), cystic hygroma (21.4%), increased nuchal translucency (15.4%), cardiac abnormalities (15.2%), and ventriculomegaly (13.3%).

Article Details

Keywords

Ultrasound markers, trisomy 21

References

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