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Published: 2024-09-27
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DOI: https://doi.org/10.52852/tcncyh.v181i8.2634
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Vol. 181 No. 8 (2024)
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Nhi, P. T. P., Phúc, Đỗ G., & Hải, H. B. (2024). 9. Mortality rate of patients with acute pulmonary embolism and related factors at Hanoi Medical University Hospital. Journal of Medical Research, 181(8), 79-88. https://doi.org/10.52852/tcncyh.v181i8.2634

9. Mortality rate of patients with acute pulmonary embolism and related factors at Hanoi Medical University Hospital

Pham Thi Phuong Nhi, Do Giang Phuc, Hoang Bui Hai

Main Article Content

Abstract

This study was conducted to determine the relationship between CONUT score and clinical outcomes in patients receiving treatment at Military Hospital 103 for multiple myeloma. A case control study was conducted on 61 patients treated for multiple myeloma at Military Hospital 103 from January 2014 to June 2024. 85.7% of patients in the CONUT ≤ 4 group had disease control compared to 73.1% of patients who had disease control in the CONUT > 4 group, with p = 0.038. Patients in the CONUT > 4 group were 2,779 times more at risk of passing than those in the CONUT ≤ 4 group. Progressions-free survival (PFS) and overall survival (OS) of the CONUT > 4 group were 11.9 months and 19.6 months, respectively, which were statistically significantly shorter compared to PFS (30.5 months) and (OS = 63.7 months) of the CONUT ≤ 4 group, with values of p = 0.041 and p = 0.002, respectively. With p = 0.018, the CONUT score's sensitivity, specificity, and AUC for predicting OS were 59.4%, 75.9%, and 0.677, respectively. CONUT score is a factor that could predict the effectiveness of treatment response and OS in patients with multiple myeloma.

Article Details

Keywords

Acute pulmonary embolism, pulmonary embolism, three-month treatment outcome, three-month mortality

References

1. Smith SB, Geske JB, Kathuria P, et al. Analysis of National Trends in Admissions for Pulmonary Embolism. Chest. 2016; 150(1): 35-45. doi:10.1016/j.chest.2016.02.638.
2. Næss IA, Christiansen SC, Romundstad P, Cannegieter SC, Rosendaal FR, Hammerstrøm J. Incidence and mortality of venous thrombosis: a population-based study. Journal of Thrombosis and Haemostasis. 2007; 5(4): 692-699. doi:10.1111/j.1538-7836.2007.02450.x.
3. Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS): The Task Force for the diagnosis and management of acute pulmonary embolism of the European Society of Cardiology (ESC). Eur Respir J. 2019; 54(3): 1901647. doi:10.1183/13993003.01647-2019.
4. Klok FA, Ageno W, Ay C, et al. Optimal follow-up after acute pulmonary embolism: a position paper of the European Society of Cardiology Working Group on Pulmonary Circulation and Right Ventricular Function, in collaboration with the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology, endorsed by the European Respiratory Society. Eur Heart J. 2022; 43(3): 183-189. doi:10.1093/eurheartj/ehab816.
5. Đỗ Giang Phúc Lê Thị Quỳnh Trang, Hoàng Bùi Hải. Triệu chứng lâm sàng và tỷ lệ tử vong của bệnh nhân tắc động mạch phổi cấp: Một nghiên cứu đa trung tâm tại Việt Nam. Tạp chí Nghiên cứu Y học. 2022; 156(8): 111-119. doi:https://doi.org/10.52852/tcncyh.v156i8.1006.
6. Ngô Thị Nhàn, Lê Văn Cường, Nguyễn Ngọc Quang, Hoàng Bùi Hải. Đánh giá thay đổi trên siêu âm Doppler tim sau 3 tháng điều trị ở bệnh nhân tắc động mạch phổi cấp. Tạp chí Nghiên cứu Y học. 12-2020. Số 134 (10): 16 - 21.
7. Nguyễn Văn Trí, Đinh Thị Thu Hương, Nguyễn Văn Hiền. Khuyến cáo về chẩn đoán, điều trị và dự phòng thuyên tắc huyết khối tĩnh mạch của Hội Tim mạch học quốc gia Việt Nam. Nhà xuất bản Y học. 2016.
8. Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). European Heart Journal. 2020;41(4):543-603. doi:10.1093/eurheartj/ehz405
9. Humbert M, Kovacs G, Hoeper MM, et al. 2022 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J. 2023; 61(1): 2200879. doi:10.1183/13993003.00879-2022
10. den Exter PL, van der Hulle T, Lankeit M, Huisman MV, Klok FA. Long-term clinical course of acute pulmonary embolism. Blood Rev. 2013; 27(4): 185-192. doi:10.1016/j.blre.2013.06.003.
11. Peris M, López-Nuñez JJ, Maestre A, et al. Clinical characteristics and 3-month outcomes in cancer patients with incidental versus clinically suspected and confirmed pulmonary embolism. Eur Respir J. 2021; 58(1): 2002723. doi:10.1183/13993003.02723-2020.
12. Polo Friz H, Corno V, Orenti A, et al. Comorbidity assessment as predictor of short and long-term mortality in elderly patients with hemodynamically stable acute pulmonary embolism. J Thromb Thrombolysis. 2017; 44(3): 316-323. doi:10.1007/s11239-017-1540-y.
13. Wicki J, Perrier A, Perneger TV, Bounameaux H, Junod AF. Predicting adverse outcome in patients with acute pulmonary embolism: a risk score. Thromb Haemost. 2000; 84(4): 548-552.
14. Klok FA, Zondag W, van Kralingen KW, et al. Patient outcomes after acute pulmonary embolism. A pooled survival analysis of different adverse events. Am J Respir Crit Care Med. 2010; 181(5): 501-506. doi:10.1164/rccm.200907-1141OC.
15. Zeng W, Xu B, Wang X, et al. Identification of Prognostic Factors for Recurrence and Mortality in Patients With Acute Pulmonary Embolism. The Heart Surgery Forum. 2022; 25: E812-E821. doi:10.1532/hsf.4971.